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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GLI family zinc finger 1
Summary
- Gene Symbol
-
- GLI1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Cytoplasm
- DNA-binding
- Developmental protein
- Differentiation
- Disease variant
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Repeat
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cell population proliferation | ||
| smoothened signaling pathway | ||
| response to wounding | ||
| dorsal/ventral pattern formation | ||
| proximal/distal pattern formation |
GO Hierarchy
biological process
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ciliary tip | ||
| ciliary base | ||
| nucleoplasm | ||
| GLI-SUFU complex | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA binding | ||
| chromatin binding | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Zinc finger protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Zinc finger C2H2 superfamily |
| Zinc finger C2H2-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5593 | gastric papillary adenocarcinoma | |
| DOID:0050338 | primary bacterial infectious disease | |
| DOID:0060071 | pre-malignant neoplasm | |
| DOID:0080016 | spina bifida | |
| DOID:2377 | multiple sclerosis | |
| DOID:2512 | nevoid basal cell carcinoma syndrome | |
| DOID:3121 | gallbladder cancer | |
| DOID:6595 | gastric tubular adenocarcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9282 | ocular hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14632 | MGI:95727 | MOUSE00877 | ||
| 43767 | FB:FBgn0004859 | |||
| 140589 | RGD:621673 | RATNO38021 | ||
| 176548 | WB:WBGene00006604 | |||
| 352930 | ZFIN:ZDB-GENE-030321-1 | |||
| 398350 | Xenbase:XB-GENE-864895 | |||
| 481126 | CANLF01343 | |||
| 517588 | BOVIN29572 | |||
| 714843 | MACMU05452 | |||
| 100033937 | HORSE36336 |
