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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GLI family zinc finger 2
Summary
- Gene Symbol
-
- GLI2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Activator
- Alternative splicing
- Cilium
- Cytoplasm
- DNA-binding
- Developmental protein
- Disease variant
- Holoprosencephaly
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of T cell differentiation in thymus | ||
| ventral spinal cord development | ||
| mammary gland development | ||
| axon guidance | ||
| positive regulation of transcription, DNA-templated |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ciliary tip | ||
| ciliary base | ||
| nucleoplasm | ||
| GLI-SUFU complex | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| sequence-specific DNA binding | ||
| DNA-binding transcription factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Zinc finger protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Zinc finger C2H2 superfamily |
| Zinc finger C2H2-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050338 | primary bacterial infectious disease | |
| DOID:0080016 | spina bifida | |
| DOID:0080171 | esophageal atresia/tracheoesophageal fistula | |
| DOID:0080328 | Culler-Jones syndrome | |
| DOID:0110873 | holoprosencephaly 9 | |
| DOID:13608 | biliary atresia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 115160961 | SALTR15498 | |||
| 115403264 | SALFA50902 | |||
| 115533336 | GADMO29964 | |||
| 115588628 | SPAAU29058 | |||
| 115608516 | STRHB04156 | |||
| 116446558 | CORMO24644 | |||
| 116834029 | CHEAB07033 | |||
| 118149682 | CALJA38019 | |||
| 118282940 | SCOMX06412 | |||
| 118897681 | BALMU00013 |
