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GLI family zinc finger 3
Summary
- Gene Symbol
-
- GLI3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Cilium
- Cytoplasm
- DNA-binding
- Disease variant
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2R8YGX0 |
|
| P10071 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| oligodendrocyte differentiation | ||
| anterior/posterior pattern specification | ||
| smoothened signaling pathway | ||
| forebrain radial glial cell differentiation | ||
| embryonic digestive tract morphogenesis |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of leukocyte activation [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription repressor complex | ||
| nuclear speck | ||
| ciliary tip | ||
| intracellular membrane-bounded organelle | ||
| ciliary base |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| histone deacetylase binding | ||
| protein binding | ||
| histone acetyltransferase binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| chromatin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Zinc finger protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Zinc finger C2H2 superfamily |
| Zinc finger C2H2-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050338 | primary bacterial infectious disease | |
| DOID:0060071 | pre-malignant neoplasm | |
| DOID:10892 | hypospadias | |
| DOID:11193 | syndactyly | |
| DOID:1148 | polydactyly | |
| DOID:11836 | clubfoot | |
| DOID:13714 | anodontia | |
| DOID:14761 | Greig cephalopolysyndactyly syndrome | |
| DOID:5082 | liver cirrhosis | |
| DOID:9248 | Pallister-Hall syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14634 | MGI:95729 | MOUSE12044 | ||
| 43767 | FB:FBgn0004859 | |||
| 140588 | RGD:620272 | RATNO12703 | ||
| 176548 | WB:WBGene00006604 | |||
| 397837 | Xenbase:XB-GENE-865509 | |||
| 403042 | ZFIN:ZDB-GENE-041111-162 | DANRE25951 | ||
| 463369 | 9598_0:0022ff | PANTR40101 | ||
| 483244 | CANLF05498 | |||
| 702494 | MACMU33299 | |||
| 785371 | BOVIN28285 |
