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G protein subunit alpha i2

Summary

Gene Symbol

GNAI2

Organism

Homo sapiens (human)

External Links

NCBI Gene

2771

PubChem

2771

Alliance of Genome Resources

HGNC:4385

Annotation

Keyword

3D-structure
ADP-ribosylation
Alternative splicing
Cell division
Cell membrane
Cytoskeleton
GTP-binding
Magnesium
Metal-binding
Myristate
Palmitate
Reference proteome
Transducer

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B3KP24
B3KX51	Adenylate cyclase-inhibiting G alpha protein
P04899	Adenylate cyclase-inhibiting G alpha protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	21079996
positive regulation of neural precursor cell proliferation	IEA
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IBA
cell population proliferation	IEA
positive regulation of superoxide anion generation	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

signal transduction

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

regulation of urine volume [inference]

positive regulation of urine volume

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

response to nutrient

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

signaling [inference]

cell-cell signaling [inference]

gamma-aminobutyric acid signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of neural precursor cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of multicellular organismal process [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

regulation of cellular response to insulin stimulus [inference]

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

purinergic nucleotide receptor signaling pathway [inference]

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled purinergic receptor signaling pathway [inference]

G protein-coupled adenosine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

regulation of insulin receptor signaling pathway [inference]

positive regulation of insulin receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

negative regulation of synaptic transmission

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of neural precursor cell proliferation

regulation of smooth muscle cell proliferation [inference]

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

regulation of vascular associated smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

regulation of neural precursor cell proliferation [inference]

positive regulation of neural precursor cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of smooth muscle cell proliferation [inference]

positive regulation of vascular associated smooth muscle cell proliferation

positive regulation of neural precursor cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of ERK1 and ERK2 cascade

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

negative regulation of apoptotic signaling pathway

negative regulation of synaptic transmission

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of cellular response to insulin stimulus [inference]

positive regulation of cellular response to insulin stimulus [inference]

positive regulation of insulin receptor signaling pathway

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of regulated secretory pathway [inference]

regulation of calcium ion-dependent exocytosis [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

negative regulation of secretion by cell [inference]

negative regulation of exocytosis [inference]

negative regulation of regulated secretory pathway [inference]

negative regulation of calcium ion-dependent exocytosis

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

regulation of biological quality [inference]

regulation of body fluid levels [inference]

regulation of urine volume [inference]

positive regulation of urine volume

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of cyclase activity [inference]

negative regulation of adenylate cyclase activity

negative regulation of lyase activity [inference]

negative regulation of adenylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

negative regulation of cyclase activity [inference]

negative regulation of adenylate cyclase activity

regulation of adenylate cyclase activity [inference]

negative regulation of adenylate cyclase activity

negative regulation of catalytic activity [inference]

negative regulation of cyclase activity [inference]

negative regulation of adenylate cyclase activity

negative regulation of lyase activity [inference]

negative regulation of adenylate cyclase activity

regulation of lyase activity [inference]

regulation of adenylate cyclase activity [inference]

negative regulation of adenylate cyclase activity

negative regulation of lyase activity [inference]

negative regulation of adenylate cyclase activity

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
extracellular vesicle	HDA	24769233
neuronal dense core vesicle	IEA
midbody	IDA	17635935
plasma membrane	IDA TAS	17635935

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

heterotrimeric G-protein complex

catalytic complex [inference]

GTPase complex [inference]

heterotrimeric G-protein complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane

plasma membrane

cell junction [inference]

synapse

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

midbody

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

dense core granule [inference]

neuronal dense core vesicle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

cell body

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GO Term	Evidence Code	PMID
protein binding	IPI	16189514 16782902 18599439 23773523 25241761 25416956 28219978 32296183 33961781 35271311
G-protein beta/gamma-subunit complex binding	IBA
GTPase activity	IBA
G protein-coupled receptor binding	IBA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

signaling receptor binding [inference]

G protein-coupled receptor binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

G-protein beta/gamma-subunit complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha subunit

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
G protein-coupled receptor binding
G-protein beta/gamma-subunit complex binding
GTP binding
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
guanyl nucleotide binding
nucleotide binding

Displaying **all 3** entries
InterPro
G protein alpha subunit, helical insertion
Guanine nucleotide binding protein (G-protein), alpha subunit
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0110887	inflammatory bowel disease 12	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1858	McCune Albright syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	14678	MGI:95772	MOUSE61358
Drosophila melanogaster	38765	FB:FBgn0001104
Rattus norvegicus	81664	RGD:620243	RATNO41188
Caenorhabditis elegans	171675	WB:WBGene00001678
Bos taurus	281791		BOVIN17805
Danio rerio	327650	ZFIN:ZDB-GENE-030131-5861
Danio rerio	336421	ZFIN:ZDB-GENE-030131-8365
Xenopus tropicalis	394861	Xenbase:XB-GENE-6050844
Sus scrofa	397523		PIGXX04131
Canis lupus familiaris	442957		CANLF07484

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements