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colony stimulating factor 2

Summary

Gene Symbol

CSF2

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281095
PubChem: 281095

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P11052	Colony-stimulating factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of trophectodermal cell proliferation
interferon-tau production
myeloid cell differentiation	IEA	30032202
immune response	IEA	22301074 30032202

GO Hierarchy

biological process

immune system process [inference]

immune response

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation

multicellular organismal process [inference]

cytokine production [inference]

type I interferon production [inference]

interferon-tau production

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation

response to stimulus [inference]

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of trophectodermal cell proliferation [inference]

positive regulation of trophectodermal cell proliferation

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of trophectodermal cell proliferation

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of trophectodermal cell proliferation [inference]

positive regulation of trophectodermal cell proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of trophectodermal cell proliferation

regulation of trophectodermal cell proliferation [inference]

positive regulation of trophectodermal cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of trophectodermal cell proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
granulocyte macrophage colony-stimulating factor receptor binding	IEA	22301074 30032202
cytokine activity	IEA	30032202
growth factor activity	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

granulocyte macrophage colony-stimulating factor receptor binding

receptor ligand activity [inference]

growth factor receptor binding [inference]

granulocyte macrophage colony-stimulating factor receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Granulocyte-macrophage colony-stimulating factor

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cytokine activity
granulocyte macrophage colony-stimulating factor receptor binding
growth factor activity
immune response
myeloid cell differentiation

Displaying **all 2** entries
InterPro
Four-helical cytokine-like, core
Granulocyte-macrophage colony-stimulating factor

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	1437		HUMAN80641
Mus musculus	12981		MOUSE05421
Rattus norvegicus	116630		RATNO00137
Sus scrofa	397208	9823_0:000697	PIGXX19699
Canis lupus familiaris	403923		CANLF02081
Ovis aries	443400	9940_0:001be6	SHEEP16505
Pan troglodytes	471627		PANTR36106
Felis catus	493805		FELCA02162
Macaca mulatta	574371		MACMU37808
Equus caballus	100033981		HORSE08749

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements