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integrin subunit alpha V

Summary

Gene Symbol

ITGAV

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 281875
PubChem: 281875

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Integrin
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P80746	Vitronectin receptor subunit alpha
A0A3Q1MXS2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IEA	30032202
cell-cell adhesion	IEA	30032202
cell adhesion mediated by integrin	IEA	30032202
integrin-mediated signaling pathway	IEA	30032202
angiogenesis	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

blood vessel development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
integrin alphav-beta8 complex
focal adhesion
integrin alphav-beta6 complex
integrin complex	IEA	22301074 30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
integrin binding	IEA	30032202
metal ion binding
virus receptor activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

exogenous protein binding [inference]

virus receptor activity

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 7** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin domain superfamily

Ortholog

Displaying entries **11 - 20** of 92 in total

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Species	Gene ID	Orthologous MAtrix
Ornithorhynchus anatinus	100085661	ORNAN26751
Danio rerio	100151255	DANRE45382
Taeniopygia guttata	100228982	TAEGU28539
Callithrix jacchus	100389906	CALJA38324
Pongo abelii	100451792	PONAB24455
Meleagris gallopavo	100541922	MELGA11900
Anolis carolinensis	100567819	ANOCA11739
Nomascus leucogenys	100604485	NOMLE21569
Loxodonta africana	100671252	LOXAF18873
Oreochromis niloticus	100697617	ORENI21256