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ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Summary

Gene Symbol

ST3GAL1

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 282351
KEGG Gene ID: bta:282351
PubChem: 282351

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A5D960	Gal-NAc6S Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase Monosialoganglioside sialyltransferase ST3Gal I ST3GalA.1 ST3O Sialyltransferase 4A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein glycosylation	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

Displaying 1 entry
GO Term	Evidence Code	PMID
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

beta-galactoside (CMP) alpha-2,3-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00780

Name

beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.3.2 2.4.3.4]

References

1383214

Reactions

Displaying **all 5** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05913	2.4.3.4	G00031MO	G65562ZE
R05967	2.4.3.2	G99053DY	G32254QI
R05949	2.4.3.2	G37184KW	G40183QN
R05942	2.4.3.2	G48558GR	G46677TE
R05957	2.4.3.2	G21856LC	G03277YI

Rhea

RHEA:21616

a β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl derivative + H⁺ + CMP

Enzyme

2.4.3.4

PMID

RHEA:52380

a β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl derivative + H⁺ + CMP

Enzyme

2.4.3.2

PMID

RHEA:18021

CMP-N-acetyl-β-neuraminate + a ganglioside GM1 (d18:1(4E))

H⁺ + CMP + a ganglioside GD1a (d18:1(4E))

Enzyme

2.4.3.2

PMID

Ortholog

Displaying entries **21 - 30** of 65 in total

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Species	Gene ID	Orthologous MAtrix
Canis lupus familiaris	482050	CANLF03231
Vulpes vulpes	112915992	VULVU08249
Ursus americanus	123801924	URSAM06120
Ailuropoda melanoleuca	100467054	AILME15985
Mustela putorius furo	101675267	MUSPF17253
Panthera leo	122211070	PANLE18695
Tursiops truncatus	101326842	TURTR08337
Balaenoptera musculus	118883441	BALMU01232
Loxodonta africana	100667581	LOXAF16560
Equus caballus	100069007	HORSE42812

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements