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hydroxysteroid 11-beta dehydrogenase 1

Summary

Gene Symbol

HSD11B1

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 282589
KEGG Gene ID: bta:282589
PubChem: 282589

Annotation

Keyword

Endoplasmic reticulum
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8HZJ8	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1
A0A8K3KFT3	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
steroid catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

lipid catabolic process [inference]

steroid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IEA	30032202
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
steroid binding	IEA	30032202
11-beta-hydroxysteroid dehydrogenase (NADP+) activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [inference]

11-beta-hydroxysteroid dehydrogenase (NADP+) activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [inference]

11-beta-hydroxysteroid dehydrogenase (NADP+) activity

binding [inference]

lipid binding [inference]

steroid binding

organic cyclic compound binding [inference]

steroid binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K15680

Name

corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]

References

Rhea

RHEA:11388

an 11β-hydroxysteroid + NADP⁺

H⁺ + an 11-oxosteroid + NADPH

Enzyme

1.1.1.146

PMID

RHEA:20233

a 7β-hydroxysteroid + NADP⁺

H⁺ + a 7-oxosteroid + NADPH

Enzyme

1.1.1.201

PMID

Ortholog

Displaying entries **51 - 60** of 72 in total

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Species	Gene ID	Orthologous MAtrix
Aotus nancymaae	105722070	AOTNA01489
Phascolarctos cinereus	110222669	PHACI12627
Saimiri boliviensis boliviensis	101040472	SAIBB17379
Ictidomys tridecemlineatus	101971234	ICTTR05853
Jaculus jaculus	101597965	JACJA04475
Myotis lucifugus	102439972	MYOLU05748
Rhinolophus ferrumequinum	117015114	RHIFE26105
Taeniopygia guttata	100222111	TAEGU15038
Taeniopygia guttata	100225021	TAEGU15038
Chlorocebus sabaeus	103230154	CHLSB11981

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements