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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
C-X-C motif chemokine receptor 3
Summary
- Gene Symbol
-
- CXCR3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Apoptosis
- Cell membrane
- Chemotaxis
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Sulfation
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P49682 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chemotaxis | ||
| positive regulation of cell population proliferation | ||
| positive regulation of chemotaxis | ||
| regulation of cell adhesion | ||
| positive regulation of angiogenesis |
GO Hierarchy
- regulation of cell adhesion
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| cell surface | ||
| cytoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| chemokine receptor activity | ||
| signaling receptor activity | ||
| C-X-C chemokine binding | ||
| C-X-C chemokine receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- C-X-C motif chemokine receptor 3
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050073 | invasive aspergillosis | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:13406 | pulmonary sarcoidosis | |
| DOID:14004 | thoracic aortic aneurysm | |
| DOID:1485 | cystic fibrosis | |
| DOID:1591 | renovascular hypertension | |
| DOID:2841 | asthma | |
| DOID:3070 | high grade glioma | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3525 | middle cerebral artery infarction |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 12766 | MGI:1277207 | MOUSE66733 | ||
| 84475 | RGD:621528 | RATNO44460 | ||
| 188226 | WB:WBGene00011578 | |||
| 443669 | Xenbase:XB-GENE-5819828 | |||
| 465704 | 9598_0:0058d8 | PANTR46273 | ||
| 491952 | CANLF19881 | |||
| 496477 | Xenbase:XB-GENE-5819824 | |||
| 497018 | BOVIN36890 | |||
| 654692 | ZFIN:ZDB-GENE-060130-38 | |||
| 699438 | MACMU48616 |
