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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phosphatidylinositol glycan anchor biosynthesis class W
Summary
- Gene Symbol
-
- PIGW
- Aliases
-
- FLJ37433
- GPI-anchored wall protein transfer 1 homolog (S. cerevisiae)
- Gwt1
- PIG-W
- Organism
- Homo sapiens (human)
External Links
- NCBI Gene
- 284098
- GGDB ID
- HGNC
- 23213
- mRNA
- map
-
- 17q12, 17q21.1 (HGNC)
- Protein
- OMIM
- KEGG Gene ID
- hsa:284098
- PubChem
- 284098
- Alliance of Genome Resources
Annotation
- Keyword
-
- Acyltransferase
- Disease variant
- Endoplasmic reticulum
- GPI-anchor biosynthesis
- Glycoprotein
- Intellectual disability
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q7Z7B1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein localization to plasma membrane | ||
| GPI anchor biosynthetic process | ||
| GPI anchor metabolic process | ||
| preassembly of GPI anchor in ER membrane |
|
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucosaminyl-phosphatidylinositol O-acyltransferase activity | ||
| O-acyltransferase activity |
|
GO Hierarchy
GlycoGene Database (GGDB)
- GGDB ID
- gg220
- Gene Symbol
-
- PIGW
KEGG BRITE Database
G94923PG
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050562 | West syndrome | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050841 | focal hand dystonia | |
| DOID:0060216 | Cogan syndrome | |
| DOID:0060249 | scoliosis | |
| DOID:0060823 | syndromic X-linked intellectual disability 94 | |
| DOID:0070432 | hyperphosphatasia with impaired intellectual development syndrome 5 | |
| DOID:10293 | monocular esotropia | |
| DOID:10487 | Hirschsprung's disease | |
| DOID:1059 | intellectual disability |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000023 | Inguinal hernia |
| HP:0000126 | Hydronephrosis |
| HP:0000158 | Macroglossia |
| HP:0000193 | Bifid uvula |
| HP:0000218 | High palate |
| HP:0000248 | Brachycephaly |
| HP:0000280 | Coarse facial features |
| HP:0000286 | Epicanthus |
| HP:0000289 | Broad philtrum |
| Disease ID | Disease Name |
|---|---|
| OMIM:616025 |
|
| ORPHA:247262 |
|
PubChem Disease
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002101
- Gene Name
- phosphatidylinositol glycan anchor biosynthesis, class W
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 190940 | WB:WBGene00022447 | ||
| 33425 | FB:FBgn0031422 | ||
| 38220 | FB:FBgn0035265 | ||
| 103180633 | CALMI20883 | ||
| 102360961 | LATCH19794 | ||
| 100136853 | ZFIN:ZDB-GENE-080204-94 | DANRE36465 | |
| 103043659 | ASTMX09639 | ||
| 108259696 | ICTPU23177 | ||
| 113577563 | ELEEL19637 | ||
| 106603973 | SALSA28363 |
