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melanin concentrating hormone receptor 1

Summary

Gene Symbol

MCHR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2847

PubChem

2847

Alliance of Genome Resources

HGNC:4479

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99705	G-protein coupled receptor 24 MCH-1R SLC-1 Somatostatin receptor-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
generation of precursor metabolites and energy	TAS	10421367
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS	10421368
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	TAS	10421367
positive regulation of cytosolic calcium ion concentration	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

cellular metabolic process [inference]

generation of precursor metabolites and energy

multicellular organismal process [inference]

behavior [inference]

feeding behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

neuropeptide signaling pathway

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IBA
cilium	IDA	28154160
neuron projection	IBA
ciliary membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

non-motile cilium

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

cilium

non-motile cilium

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
signaling receptor binding	IEA
neuropeptide receptor activity	TAS	10860944
melanin-concentrating hormone receptor activity	IEA
hormone binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

amide binding [inference]

peptide binding [inference]

neuropeptide binding

hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

melanin-concentrating hormone receptor activity

protein-hormone receptor activity [inference]

melanin-concentrating hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
neuropeptide binding
neuropeptide signaling pathway

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:11981	morbid obesity	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	2847	Xenbase:XB-GENE-1018376
Xenopus tropicalis	83567	Xenbase:XB-GENE-1018376
Xenopus tropicalis	176124	Xenbase:XB-GENE-1018376
Xenopus tropicalis	207911	Xenbase:XB-GENE-1018376

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements