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MIRAGE
ankyrin 2
Summary
- Gene Symbol
-
- ANK2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Alternative splicing
- Cell membrane
- Cytoplasm
- Cytoskeleton
- Disease variant
- Endocytosis
- Endosome
- Long QT syndrome
- Lysosome
- Membrane
- Mitochondrion
- Phosphoprotein
- Postsynaptic cell membrane
- Protein transport
- Proteomics identification
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| E9PCH6 |
|
| A0A5F9ZI69 |
|
| A0A5F9ZI16 |
|
| A0A5F9ZH70 |
|
| A0A5F9ZHQ3 |
|
| A0A5F9ZGZ1 |
|
| A0A5F9ZI08 |
|
| A0A5F9ZHL9 |
|
| A0A5F9ZH17 |
|
| A0A5F9ZI81 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of heart rate | ||
| atrial septum development | ||
| intracellular calcium ion homeostasis | ||
| endocytosis | ||
| cytoskeleton organization |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
regulation of metal ion transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
positive regulation of biological process [inference]
positive regulation of cellular process [inference]
positive regulation of transport [inference]
regulation of cellular process [inference]
regulation of transmembrane transport [inference]
regulation of transmembrane transporter activity [inference]
positive regulation of transmembrane transport [inference]
regulation of monoatomic ion transmembrane transport [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| lysosome | ||
| early endosome | ||
| cytosol | ||
| cytoskeleton |
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural constituent of cytoskeleton | ||
| protein binding | ||
| cytoskeletal anchor activity | ||
| enzyme binding | ||
| protein kinase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ankyrin
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ankyrin repeat-containing domain superfamily |
| Ankyrin repeat |
| Ankyrin, UPA domain |
| Death domain |
| Death-like domain superfamily |
| ZU5 domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060224 | atrial fibrillation | |
| DOID:0111700 | ankyrin-B-related cardiac arrhythmia | |
| DOID:13884 | sick sinus syndrome | |
| DOID:2843 | long QT syndrome |
