GlyCosmos Portal

Submissions

NADH:ubiquinone oxidoreductase core subunit S2

Summary

Gene Symbol

Ndufs2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

289218

PubChem

289218

Alliance of Genome Resources

RGD:1307109

Annotation

Keyword

4Fe-4S
Acetylation
Methylation
Mitochondrion inner membrane
NAD
Oxidoreductase
Reference proteome
Respiratory chain
Transit peptide
Translocase
Ubiquinone

Proteins

Displaying 1 entry
UniProt	Protein Name
Q641Y2	Complex I-49kD NADH-ubiquinone oxidoreductase 49 kDa subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 17 in total

« First

‹ Prev

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
gliogenesis	ISO
mitochondrial ATP synthesis coupled electron transport	ISO
neural precursor cell proliferation	ISS
neural precursor cell proliferation	ISO
cellular response to oxygen levels	ISO

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

ATP synthesis coupled electron transport [inference]

mitochondrial ATP synthesis coupled electron transport

cellular process [inference]

cell population proliferation [inference]

neural precursor cell proliferation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

ATP synthesis coupled electron transport [inference]

mitochondrial ATP synthesis coupled electron transport

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

gliogenesis

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

gliogenesis

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

response to abiotic stimulus [inference]

response to oxygen levels [inference]

cellular response to oxygen levels

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleoplasm
mitochondrion	ISO
mitochondrial inner membrane	ISO
mitochondrial inner membrane	IDA	30922174
respiratory chain complex I	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

NADH dehydrogenase complex [inference]

respiratory chain complex I

respiratory chain complex [inference]

respiratory chain complex I

transmembrane transporter complex [inference]

respiratory chain complex I

catalytic complex [inference]

oxidoreductase complex [inference]

NADH dehydrogenase complex [inference]

respiratory chain complex I

transporter complex [inference]

transmembrane transporter complex [inference]

respiratory chain complex I

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
NADH dehydrogenase activity	ISO
NADH dehydrogenase (ubiquinone) activity	ISS
NADH dehydrogenase (ubiquinone) activity	ISO
NADH dehydrogenase (ubiquinone) activity	IMP	30922174
oxidoreductase activity, acting on NAD(P)H	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity [inference]

NADH dehydrogenase (ubiquinone) activity

oxidoreductase activity, acting on NAD(P)H

NADH dehydrogenase activity

NADH dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (ubiquinone) activity

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [inference]

NAD(P)H dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (quinone) activity [inference]

NADH dehydrogenase (ubiquinone) activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

oxidoreduction-driven active transmembrane transporter activity [inference]

NADH dehydrogenase (ubiquinone) activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

ion binding [inference]

cation binding [inference]

metal ion binding

quinone binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

small molecule sensor activity [inference]

oxygen sensor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

NADH:ubiquinone oxidoreductase

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
mitochondrial electron transport, NADH to ubiquinone
oxidoreductase activity, acting on NAD(P)H
quinone binding

Displaying **all 4** entries
InterPro
NAD(P)H-quinone oxidoreductase subunit D/H
NADH-quinone oxidoreductase, subunit D
NADH
[NiFe]-hydrogenase, large subunit

Ortholog

Displaying entries **21 - 30** of 74 in total

« First

‹ Prev

1

2

3

4

5

6

7

8

Next ›

Last »
Species	Gene ID	Orthologous MAtrix
Cricetulus griseus	100768067	CRIGR15975
Sarcophilus harrisii	100922998	SARHA08043
Otolemur garnettii	100949204	OTOGA15528
Pan paniscus	100978992	PANPA02943
Papio anubis	101002291	PAPAN21521
Saimiri boliviensis boliviensis	101049213	SAIBB29369
Takifugu rubripes	101073744	TAKRU48731
Felis catus	101088298	FELCA36364
Oryzias latipes	101168577	ORYLA07674
Tursiops truncatus	101331909	TURTR12851