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glutamate ionotropic receptor delta type subunit 1

Summary

Gene Symbol

GRID1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2894

PubChem

2894

Alliance of Genome Resources

HGNC:4575

JoGo

GRID1

TogoVar

GRID1

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8KAN9
Q9ULK0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
phospholipase C-activating G protein-coupled receptor signaling pathway	IDA	27276689
glutamate receptor signaling pathway
negative regulation of synaptic plasticity	IDA	38060673
ion transmembrane transport	IEA
monoatomic ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

synaptic signaling via neuropeptide

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway

ionotropic glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport

multicellular organismal process [inference]

behavior [inference]

social behavior

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

negative regulation of synaptic plasticity

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

synaptic signaling via neuropeptide

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

glutamate receptor signaling pathway

ionotropic glutamate receptor signaling pathway

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

ligand-gated ion channel signaling pathway [inference]

ionotropic glutamate receptor signaling pathway

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

negative regulation of synaptic plasticity

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of postsynapse organization

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential

regulation of synaptic plasticity [inference]

negative regulation of synaptic plasticity

regulation of postsynaptic membrane neurotransmitter receptor levels

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
AMPA glutamate receptor complex	IBA
dendritic spine	IBA
postsynaptic membrane	ISS
postsynaptic membrane	IDA	38060673

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

neurotransmitter receptor complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

trans-synaptic protein complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

ionotropic glutamate receptor complex [inference]

AMPA glutamate receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
AMPA glutamate receptor activity	IBA
protein binding	IPI	28514442 33961781
glutamate receptor activity
GABA receptor activity	IDA	38060673
identical protein binding	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

AMPA glutamate receptor activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

amide transmembrane transporter activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

salt transmembrane transporter activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

binding [inference]

protein binding

identical protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential

glutamate receptor activity

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

GABA receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

glutamate-gated receptor activity [inference]

AMPA glutamate receptor activity

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

postsynaptic neurotransmitter receptor activity [inference]

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

glutamate receptor

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
glutamate receptor activity
ligand-gated monoatomic ion channel activity
modulation of chemical synaptic transmission
monoatomic ion channel activity
monoatomic ion transport
synaptic transmission, glutamatergic
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Displaying **all 5** entries
InterPro
Ionotropic glutamate receptor, C-terminal
Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Ionotropic glutamate receptor, metazoa
Ionotropic glutamate receptor
Periplasmic binding protein-like I