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glutamate ionotropic receptor delta type subunit 2
Summary
- Gene Symbol
-
- GRID2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Neurodegeneration
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O43424 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of postsynaptic membrane neurotransmitter receptor levels | ||
| regulation of neuron apoptotic process | ||
| excitatory synapse assembly | ||
| regulation of neuron projection development | ||
| glutamate receptor signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| postsynaptic density membrane | ||
| parallel fiber to Purkinje cell synapse | ||
| plasma membrane | ||
| dendritic spine | ||
| ionotropic glutamate receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| glutamate receptor activity | ||
| identical protein binding | ||
| transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | ||
| PDZ domain binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Ionotropic glutamate receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080042 | autosomal recessive spinocerebellar ataxia 18 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14804 | MGI:95813 | MOUSE49768 | ||
| 31867 | FB:FBgn0052704 | |||
| 33683 | FB:FBgn0031634 | |||
| 79220 | RGD:68368 | RATNO31632 | ||
| 448841 | ZFIN:ZDB-GENE-040913-1 | DANRE42510 | ||
| 487863 | CANLF13076 | |||
| 704787 | MACMU36396 | |||
| 743067 | 9598_0:001516 | PANTR34123 | ||
| 100078083 | ORNAN03801 | |||
| 100227368 | TAEGU24332 |
