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acyl-CoA dehydrogenase family member 9

Summary

Gene Symbol

ACAD9

Organism

Homo sapiens (human)

External Links

NCBI Gene

28976

PubChem

28976

Alliance of Genome Resources

HGNC:21497

Annotation

Keyword

3D-structure
Acetylation
Disease variant
FAD
Mitochondrion inner membrane
Oxidoreductase
Phosphoprotein
Primary mitochondrial disease
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9H845	Acyl-CoA dehydrogenase family member 9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
long-chain fatty acid metabolic process	IDA	16020546
medium-chain fatty acid metabolic process	IDA	16020546
mitochondrial respiratory chain complex I assembly	IMP NAS	20816094 32320651

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly [inference]

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial membrane	IDA	16020546
mitochondrial inner membrane	NAS TAS	32320651
dendrite	IDA	21237683
mitochondrion	HTP IDA	16020546 20816094 34800366
nucleus	IDA	21237683

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
long-chain-acyl-CoA dehydrogenase activity	IDA	16020546
protein binding	IPI	20816094 32320651 33753518
medium-chain-acyl-CoA dehydrogenase activity	IDA	16020546
acyl-CoA dehydrogenase activity	IBA
flavin adenine dinucleotide binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor [inference]

acyl-CoA dehydrogenase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acyl-CoA dehydrogenase

Functional Category

C: Energy production and conversion
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
fatty acid beta-oxidation using acyl-CoA dehydrogenase
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors

Displaying **all 8** entries
InterPro
Acyl-CoA dehydrogenase, conserved site
Acyl-CoA dehydrogenase-like, C-terminal
Acyl-CoA dehydrogenase/oxidase, C-terminal
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Acyl-CoA dehydrogenase/oxidase, N-terminal
Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Acyl-CoA oxidase/dehydrogenase, middle domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112072	nuclear type mitochondrial complex I deficiency 20	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	36242		FB:FBgn0086712
Caenorhabditis elegans	177654		WB:WBGene00001566
Mus musculus	229211		MGI:1914272	MOUSE36788
Rattus norvegicus	294973		RGD:727973	RATNO25577
Xenopus laevis	446728		Xenbase:XB-GENE-5885071
Pan troglodytes	460679	9598_0:001252		PANTR32129
Canis lupus familiaris	476519			CANLF07232
Xenopus tropicalis	548505		Xenbase:XB-GENE-5885005
Bos taurus	617428			BOVIN18120
Macaca mulatta	704527			MACMU28252

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OrthoDB (Group)

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Acknowledgements