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SET domain containing 2, histone lysine methyltransferase

Summary

Gene Symbol

SETD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

29072

PubChem

29072

Alliance of Genome Resources

HGNC:18420

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Antiviral defense
Autism spectrum disorder
Chromatin regulator
Chromosome
Coiled coil
DNA repair
Developmental protein
Differentiation
Disease variant
Host-virus interaction
Innate immunity
Intellectual disability
Isopeptide bond
Metal-binding
Methyltransferase
Nucleus
Phosphoprotein
Reference proteome
S-adenosyl-L-methionine
Transcription regulation
Tumor suppressor
Ubl conjugation
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9BYW2	HIF-1 Huntingtin yeast partner B Huntingtin-interacting protein 1 Huntingtin-interacting protein B Lysine N-methyltransferase 3A Protein-lysine N-methyltransferase SETD2 SET domain-containing protein 2 p231HBP

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 33 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
morphogenesis of a branching structure	IEA
neural tube closure	IEA
mismatch repair	IMP	23622243
regulation of DNA-templated transcription	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

methylation [inference]

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

macromolecule modification [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

macromolecule methylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein alkylation [inference]

protein methylation [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine methylation [inference]

peptidyl-lysine trimethylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule cytoskeleton organization involved in mitosis

cell cycle process [inference]

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

mismatch repair

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular developmental process [inference]

cell differentiation [inference]

cell development [inference]

stem cell development

cell motility [inference]

cell migration [inference]

cell migration involved in vasculogenesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule cytoskeleton organization involved in mitosis

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

nucleosome organization

multicellular organismal process [inference]

morphogenesis of a branching structure

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

skeletal system morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

coronary vasculature morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

embryonic placenta morphogenesis

tissue morphogenesis [inference]

mesoderm morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

tube formation [inference]

tube closure [inference]

neural tube closure

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

pericardium development

forebrain development

cell development [inference]

stem cell development

cellular developmental process [inference]

cell differentiation [inference]

cell development [inference]

stem cell development

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to alkaloid

response to organic cyclic compound

response to cytokine [inference]

response to type I interferon

response to inorganic substance [inference]

response to metal ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to alkaloid

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of protein localization [inference]

regulation of protein localization to chromatin

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of ossification

regulation of response to stimulus [inference]

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of transcription, DNA-templated

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

positive regulation of autophagy

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of cellular catabolic process [inference]

positive regulation of autophagy

regulation of cell division [inference]

regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of protein localization [inference]

regulation of protein localization to chromatin

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of ossification [inference]

positive regulation of ossification

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of type I interferon production [inference]

positive regulation of interferon-alpha production

positive regulation of ossification

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	IBA
nucleoplasm	TAS
chromosome	ISS
chromosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

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GO Term	Evidence Code	PMID
protein binding	IPI	17500595 19141475 21988832 28753426 36537238
protein-lysine N-methyltransferase activity	IDA	28753426
alpha-tubulin binding	IDA	27518565
metal ion binding	IEA
histone H3K36 methyltransferase activity	IDA	23043551 24843002 26002201 27474439 28753426

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity [inference]

histone H3 methyltransferase activity

histone H3K36 methyltransferase activity

histone H3K36 trimethyltransferase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

alpha-tubulin binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Histone-lysine N-methyltransferase

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
histone H3K36 methyltransferase activity
histone methyltransferase activity
methylation
transferase activity

Displaying **all 4** entries
InterPro
AWS domain
Post-SET domain
SET domain superfamily
SET domain

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0050156	idiopathic pulmonary fibrosis	Alliance of Genome Resources
DOID:0060307	autosomal dominant intellectual developmental disorder	Alliance of Genome Resources
DOID:1790	malignant mesothelioma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:4467	clear cell renal cell carcinoma	Alliance of Genome Resources
DOID:7474	malignant pleural mesothelioma	Alliance of Genome Resources
DOID:9253	gastrointestinal stromal tumor	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	2146	SGD:S000003704
Saccharomyces cerevisiae S288C	7468	SGD:S000003704
Saccharomyces cerevisiae S288C	14056	SGD:S000003704
Xenopus tropicalis	29072	Xenbase:XB-GENE-995488
Saccharomyces cerevisiae S288C	54904	SGD:S000003704
Saccharomyces cerevisiae S288C	64324	SGD:S000003704
Mus musculus	235626	Xenbase:XB-GENE-995488	MOUSE63479
Rattus norvegicus	316013		RATNO41814
Pan troglodytes	460331		PANTR30987
Canis lupus familiaris	476643		CANLF07557

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements