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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD274 molecule
Summary
- Gene Symbol
-
- CD274
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Disulfide bond
- Endosome
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of activated T cell proliferation | ||
| positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process | ||
| negative regulation of interleukin-10 production | ||
| regulation of T cell apoptotic process | ||
| negative regulation of activated T cell proliferation |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of cell adhesion [inference]
negative regulation of cell activation [inference]
negative regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
negative regulation of cell adhesion [inference]
regulation of cell-cell adhesion [inference]
negative regulation of cell-cell adhesion [inference]
regulation of leukocyte cell-cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
negative regulation of cell adhesion [inference]
negative regulation of cell activation [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte proliferation [inference]
regulation of T cell activation [inference]
regulation of T cell proliferation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| plasma membrane | ||
| nucleoplasm | ||
| actin cytoskeleton | ||
| recycling endosome membrane |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Programmed cell death 1 ligand 1
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Immunoglobulin V-set domain |
| Immunoglobulin subtype |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0080159 | Cryptococcal meningitis | |
| DOID:0080797 | nasal type extranodal NK/T-cell lymphoma | |
| DOID:10534 | stomach cancer | |
| DOID:10591 | pre-eclampsia | |
| DOID:11166 | Human papillomavirus infectious disease | |
| DOID:14115 | toxic shock syndrome | |
| DOID:1883 | hepatitis C | |
| DOID:2957 | pulmonary tuberculosis | |
| DOID:399 | tuberculosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 60533 | MGI:1926446 | MOUSE25239 | ||
| 464981 | 9598_0:002777 | PANTR43600 | ||
| 484186 | CANLF00475 | |||
| 499342 | RGD:1566211 | RATNO20393 | ||
| 533834 | BOVIN34363 | |||
| 574058 | PIGXX15493 | |||
| 716043 | MACMU13059 | |||
| 100018006 | MONDO30388 | |||
| 100051703 | HORSE21843 | |||
| 100074433 | ORNAN32309 |
