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erb-b2 receptor tyrosine kinase 3

Summary

Gene Symbol

Erbb3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29496

PubChem

29496

Alliance of Genome Resources

RGD:69323

Annotation

Keyword

ATP-binding
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Tyrosine-protein kinase

Proteins

Displaying **all 3** entries
UniProt	Protein Name
G3V6N1
Q62799	Proto-oncogene-like protein c-ErbB-3
A6KSF8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
protein phosphorylation	IEA
axonogenesis	IEP	9030624
cranial nerve development	IEA ISO
negative regulation of signal transduction	IEA ISO
Schwann cell development	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

ERBB signaling pathway

epidermal growth factor receptor signaling pathway

ERBB2 signaling pathway [inference]

ERBB2-ERBB3 signaling pathway

ERBB3 signaling pathway [inference]

ERBB2-ERBB3 signaling pathway

extrinsic apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway in absence of ligand

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway in absence of ligand

ensheathment of neurons [inference]

axon ensheathment [inference]

myelination

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

motor neuron apoptotic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

neurogenesis

cell development [inference]

glial cell development [inference]

Schwann cell development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

multicellular organismal process [inference]

multicellular organism development

tissue remodeling [inference]

mammary gland involution

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

axonogenesis

anatomical structure development [inference]

multicellular organism development

tissue development [inference]

mesenchyme development [inference]

endocardial cushion development

muscle tissue development [inference]

skeletal muscle tissue development

nerve development [inference]

cranial nerve development

cell development [inference]

glial cell development [inference]

Schwann cell development

animal organ development [inference]

sensory organ development [inference]

tongue development

system development [inference]

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

neurogenesis

cell development [inference]

glial cell development [inference]

Schwann cell development

rhythmic process [inference]

circadian rhythm

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of signal transduction

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of signaling [inference]

negative regulation of signal transduction

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of secretion [inference]

negative regulation of secretion

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

negative regulation of transport [inference]

negative regulation of secretion

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

positive regulation of developmental process [inference]

positive regulation of muscle organ development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of muscle tissue development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of multicellular organismal process [inference]

positive regulation of muscle organ development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell communication [inference]

negative regulation of signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

negative regulation of transport [inference]

negative regulation of secretion

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of signal transduction

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction

regulation of developmental process [inference]

regulation of muscle organ development [inference]

regulation of striated muscle tissue development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

regulation of cardiac muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of muscle organ development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of developmental process [inference]

positive regulation of muscle organ development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of muscle tissue development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

regulation of muscle tissue development [inference]

regulation of striated muscle tissue development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

regulation of cardiac muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

positive regulation of muscle tissue development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

ERBB signaling pathway

epidermal growth factor receptor signaling pathway

ERBB2 signaling pathway [inference]

ERBB2-ERBB3 signaling pathway

ERBB3 signaling pathway [inference]

ERBB2-ERBB3 signaling pathway

extrinsic apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway in absence of ligand

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

signal transduction in absence of ligand [inference]

extrinsic apoptotic signaling pathway in absence of ligand

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway in absence of ligand

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of signal transduction

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction

regulation of cell adhesion [inference]

negative regulation of cell adhesion

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of transmembrane transport [inference]

regulation of glucose transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of glucose import [inference]

positive regulation of glucose import

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

regulation of cell population proliferation

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of motor neuron apoptotic process [inference]

negative regulation of motor neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of calcium-mediated signaling [inference]

positive regulation of calcineurin-mediated signaling [inference]

positive regulation of calcineurin-NFAT signaling cascade

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of transmembrane transport [inference]

positive regulation of glucose transmembrane transport [inference]

positive regulation of glucose import

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell communication [inference]

negative regulation of signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of neuron apoptotic process

negative regulation of motor neuron apoptotic process

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of muscle organ development [inference]

positive regulation of striated muscle tissue development [inference]

positive regulation of cardiac muscle tissue development

regulation of biological quality [inference]

regulation of membrane permeability [inference]

positive regulation of membrane permeability

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GO Term	Evidence Code	PMID
ERBB3:ERBB2 complex	IEA ISO
basal plasma membrane	IBA
apical plasma membrane	IEA ISO
postsynaptic membrane	IDA	7589796
lateral plasma membrane	IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

ERBB3:ERBB2 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

ERBB3:ERBB2 complex

cellular anatomical entity [inference]

extracellular space

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

lateral plasma membrane

cell body [inference]

neuronal cell body

apical part of cell

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GO Term	Evidence Code	PMID
ubiquitin protein ligase binding	IEA ISO
signaling receptor activity	ISO
protein heterodimerization activity	IEA ISO
ATP binding	IEA
protein tyrosine kinase activator activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

ErbB-3 class receptor binding

growth factor binding

neuregulin binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

neuregulin receptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

receptor tyrosine-protein kinase erbB-3

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
ATP binding
kinase activity
nervous system development
neuregulin binding
neuregulin receptor activity
neurogenesis
nucleotide binding
phosphorylation
positive regulation of cell population proliferation
transferase activity

Displaying **all 10** entries
InterPro
Furin-like cysteine-rich domain
Furin-like repeat
Growth factor receptor cysteine-rich domain superfamily
Growth factor receptor domain 4
Protein kinase domain
Protein kinase-like domain superfamily
Receptor L-domain superfamily
Receptor L-domain
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine protein kinase, EGF/ERB/XmrK receptor

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
postsynaptic membrane	PMID:7589796
neuronal cell body	PMID:16859650

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources
DOID:0050861	colorectal adenocarcinoma	Alliance of Genome Resources
DOID:0050865	tongue squamous cell carcinoma	Alliance of Genome Resources
DOID:0060074	ductal carcinoma in situ	Alliance of Genome Resources
DOID:0060560	lethal congenital contracture syndrome 2	Alliance of Genome Resources
DOID:0080679	neuronal intestinal dysplasia type A	Alliance of Genome Resources
DOID:10155	intestinal cancer	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10376	amblyopia	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2065		HGNC:3431	HUMAN13405
Mus musculus	13867	10090_1:003342	MGI:95411	MOUSE01544
Drosophila melanogaster	37455		FB:FBgn0003731
Caenorhabditis elegans	174462		WB:WBGene00002299
Danio rerio	386635		ZFIN:ZDB-GENE-030916-3
Pan troglodytes	451980			PANTR05597
Danio rerio	544664		ZFIN:ZDB-GENE-050107-1
Bos taurus	785655			BOVIN29649
Oryctolagus cuniculus	100008807			RABIT10473
Monodelphis domestica	100028103			MONDO00280

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements