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solute carrier family 10 member 2

Summary

Gene Symbol

Slc10a2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29500

PubChem

29500

Alliance of Genome Resources

RGD:3682

Annotation

Keyword

Glycoprotein
Lipid transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q62633	Apical sodium-dependent bile acid transporter Ileal Na(+)/bile acid cotransporter Ileal sodium-dependent bile acid transporter Na(+)-dependent ileal bile acid transporter Sodium/taurocholate-cotransporting polypeptide, ileal Solute carrier family 10 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sodium ion transport	TAS	11509565
response to bacterium	ISO
transmembrane transport	IEA
bile acid metabolic process	TAS	15304498
bile acid and bile salt transport	IBA IDA	8770054

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

organic hydroxy compound metabolic process [inference]

bile acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
microvillus	ISO
apical plasma membrane	IBA IDA ISO	8770054
proteasome complex	IDA	15304498

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

Displaying 1 entry
GO Term	Evidence Code	PMID
bile acid:sodium symporter activity	IBA IDA TAS	11509565 8770054

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Zinc finger, RING-type

Functional Category

P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
bile acid
lipid transport
symporter activity

Displaying **all 3** entries
InterPro
Bile acid
Bile acid
Sodium/solute symporter superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
proteasome complex	PMID:15304498
apical plasma membrane	PMID:8770054

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:5295	intestinal disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **116** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6555		HGNC:10906	HUMAN17594
Mus musculus	20494	10090_1:002aa8	MGI:1201406	MOUSE59604
Drosophila melanogaster	32472		FB:FBgn0030638
Drosophila melanogaster	32621		FB:FBgn0030756
Danio rerio	393329		ZFIN:ZDB-GENE-040426-1328	DANRE44892
Pan troglodytes	467318			PANTR08053
Bos taurus	525823			BOVIN04102
Macaca mulatta	702376			MACMU16488
Caenorhabditis elegans	4363069		WB:WBGene00044650
Oryctolagus cuniculus	100009550			RABIT12570