GlyCosmos Portal

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
postsynaptic membrane	IDA	8613776
postsynapse	IBA
postsynaptic specialization membrane	IDA IEA	8613776 9464994
receptor complex	IDA	14713300
GABA-A receptor complex	IBA ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

GABA receptor complex [inference]

GABA-A receptor complex

membrane protein complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

chloride channel complex

transporter complex [inference]

transmembrane transporter complex

monoatomic ion channel complex [inference]

chloride channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

dendrite membrane

synaptic membrane [inference]

cell junction [inference]

synapse

GABA-ergic synapse

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

cerebellar Golgi cell to granule cell synapse

leading edge membrane [inference]

neuron projection membrane [inference]

dendrite membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

cell body membrane [inference]

neuronal cell body membrane

postsynapse

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
diazepam binding	IDA	2166916
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IEA ISO
GABA-A receptor activity	IBA IDA IEA	17395622
chloride channel activity	IBA IEA
GABA-gated chloride ion channel activity	IMP	17395622

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

inhibitory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

inhibitory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

inhibitory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic anion channel activity [inference]

GABA-gated chloride ion channel activity

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

GABA-gated chloride ion channel activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding

protein-containing complex binding

organic cyclic compound binding [inference]

diazepam binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

GABA receptor activity [inference]

GABA-A receptor activity

neurotransmitter receptor activity

benzodiazepine receptor activity

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

postsynaptic neurotransmitter receptor activity [inference]

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

gamma-aminobutyric acid receptor subunit alpha-6

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying entries **1 - 10** of 14 in total

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Gene Ontology
GABA-A receptor activity
GABA-gated chloride ion channel activity
benzodiazepine receptor activity
chloride channel activity
chloride transmembrane transport
chloride transport
extracellular ligand-gated monoatomic ion channel activity
gamma-aminobutyric acid signaling pathway
inhibitory extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity

Displaying entries **1 - 10** of 11 in total

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InterPro
Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain
Gamma-aminobutyric-acid A receptor, alpha 6 subunit
Gamma-aminobutyric-acid A receptor, alpha subunit
Neuronal acetylcholine receptor
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel transmembrane domain superfamily
Neurotransmitter-gated ion-channel transmembrane domain
Neurotransmitter-gated ion-channel, conserved site

Alliance of Genome Resources

Expression

Displaying **all 5** entries
Location	References
presynaptic membrane	PMID:17303643
receptor complex	PMID:14713300
neuronal cell body membrane	PMID:8613776
dendrite	PMID:8613776
postsynaptic membrane	PMID:8613776

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **81 - 90** of **124** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Castor canadensis	109678839	51338_0:0050b0
Phascolarctos cinereus	110212392		PHACI20775
Mus caroli	110304957	10089_0:003466
Mus pahari	110331564	10093_0:003345
Meriones unguiculatus	110541491	10047_0:004e30
Seriola dumerili	111234375		SERDU12555
Amphiprion ocellaris	111575937		AMPOC10555
Vulpes vulpes	112928630		VULVU02276
Astatotilapia calliptera	113030788		ASTCA02237
Anabas testudineus	113170607		ANATE07045