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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sodium voltage-gated channel alpha subunit 8
Summary
- Gene Symbol
-
- Scn8a
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cell projection
- Disulfide bond
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Ubl conjugation
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| O88420 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to toxic substance | ||
| sensory perception of sound | ||
| optic nerve development | ||
| action potential | ||
| sodium ion transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuronal cell body | ||
| voltage-gated sodium channel complex | ||
| plasma membrane | ||
| axon initial segment | ||
| dendrite |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- sodium channel protein type 8 subunit alpha
- Functional Category
-
- G: Carbohydrate transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050709 | early infantile epileptic encephalopathy | |
| DOID:0060170 | generalized epilepsy with febrile seizures plus | |
| DOID:0080422 | Dravet syndrome | |
| DOID:0080445 | developmental and epileptic encephalopathy 13 | |
| DOID:0081118 | benign familial infantile seizures 5 | |
| DOID:0111294 | generalized epilepsy with febrile seizures plus 2 | |
| DOID:1826 | epilepsy | |
| DOID:6000 | congestive heart failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 116883845 | 10117_0:000164 | |||
| 117028290 | RHIFE10079 | |||
| 117718532 | 61156_0:0032ab | |||
| 118596753 | 38674_0:003e33 | |||
| 118902485 | BALMU03621 | |||
| 119822643 | 1047088_0:003593 | |||
| 121444233 | 111838_0:005f40 | |||
| 122098404 | 105255_0:004700 | |||
| 122224564 | PANLE16578 | |||
| 123794734 | URSAM04550 |
