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OMA1 zinc metallopeptidase

Summary

Gene Symbol

Oma1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

298282

PubChem

298282

Alliance of Genome Resources

RGD:1304821

Annotation

Keyword

Autocatalytic cleavage
Disulfide bond
Lipid-binding
Metal-binding
Metalloprotease
Mitochondrion inner membrane
Reference proteome
Transit peptide
Transmembrane helix
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
D3ZS74	Overlapping with the m-AAA protease 1 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 18** of 18 in total

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GO Term	Evidence Code	PMID
mitochondrion organization	ISO
diet induced thermogenesis	IEA ISO ISS
zymogen activation	IEA ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

protein maturation [inference]

protein processing [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

protein metabolic process [inference]

protein processing [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

protein maturation [inference]

protein processing [inference]

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

lipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

protein maturation [inference]

protein processing [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein processing [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

protein maturation [inference]

protein processing [inference]

adaptive thermogenesis [inference]

diet induced thermogenesis

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

integrated stress response signaling

HRI-mediated signaling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization [inference]

cristae formation

cellular component assembly [inference]

protein-containing complex assembly [inference]

mitochondrial respiratory chain complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

mitochondrial respiratory chain complex assembly

membrane organization [inference]

mitochondrial membrane organization [inference]

inner mitochondrial membrane organization [inference]

cristae formation

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

integrated stress response signaling

HRI-mediated signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

integrated stress response signaling

HRI-mediated signaling

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of cold-induced thermogenesis

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrion organization [inference]

negative regulation of mitochondrial fusion

negative regulation of developmental process [inference]

negative regulation of mitochondrial fusion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of mitochondrial fusion [inference]

negative regulation of mitochondrial fusion

negative regulation of developmental process [inference]

negative regulation of mitochondrial fusion

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrion organization [inference]

negative regulation of mitochondrial fusion

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrion organization [inference]

negative regulation of mitochondrial fusion

regulation of mitochondrion organization [inference]

regulation of mitochondrial fusion [inference]

negative regulation of mitochondrial fusion

negative regulation of mitochondrion organization [inference]

negative regulation of mitochondrial fusion

regulation of cristae formation

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of mitochondrion organization [inference]

negative regulation of mitochondrial fusion

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IBA IEA ISO ISS
mitochondrial membrane	ISO ISS
mitochondrial intermembrane space	ISO
mitochondrion	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metalloendopeptidase activity	IBA IDA IEA ISO ISS	33200421
lipid binding	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

lipid binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **21 - 30** of 80 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Gorilla gorilla gorilla	101143884		GORGO20402
Pan paniscus	100979872		PANPA01489
Pongo abelii	100452274		PONAB17677
Homo sapiens	115209	HGNC:29661	HUMAN50105
Canis lupus familiaris	489569		CANLF15661
Vulpes vulpes	112926095		VULVU20256
Ailuropoda melanoleuca	100484088		AILME14850
Mustela putorius furo	101678232		MUSPF13956
Felis catus	101100067		FELCA19391
Panthera leo	122227362		PANLE10794

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Last updated: August 19, 2024