GlyCosmos Portal

Submissions

ALG5 dolichyl-phosphate beta-glucosyltransferase

Summary

Gene Symbol

ALG5

Aliases

bA421P11.2

Organism

Homo sapiens (human)

External Links

NCBI Gene

29880

GGDB ID

gg145

HGNC

20266

mRNA

NM_013338

map

13q13.3

Protein

NP_037470

OMIM

604565

KEGG Gene ID

hsa:29880

PubChem

29880

Alliance of Genome Resources

HGNC:20266

Annotation

Keyword

Alternative splicing
Disease variant
Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y673	Asparagine-linked glycosylation protein 5 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA IMP	10359825
protein N-linked glycosylation via asparagine	TAS
dolichol-linked oligosaccharide biosynthetic process	IMP	10359825
protein glycosylation
determination of left/right symmetry	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

multicellular organismal process [inference]

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasmic side of rough endoplasmic reticulum membrane	IGI	10359825
endoplasmic reticulum membrane	IBA TAS
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of endoplasmic reticulum membrane [inference]

cytoplasmic side of rough endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
dolichyl-phosphate beta-glucosyltransferase activity	IGI TAS	10359825
oligosaccharyl transferase activity
protein binding	IPI	32353859 32838362 33060197 36217030

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

dolichyl-phosphate beta-glucosyltransferase activity

hexosyltransferase activity [inference]

oligosaccharyl transferase activity

glucosyltransferase activity [inference]

UDP-glucosyltransferase activity [inference]

dolichyl-phosphate beta-glucosyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg145

Gene Symbol

ALG5

Orthologous Gene

Displaying **all 6** entries
Species	Protein	mRNA
Arabidopsis thaliana	NP_181493	NM_129519
Saccharomyces cerevisiae	CAA97942	Z73583
Rattus norvegicus	XP_215561	XM_215561
Drosophila melanogaster	NP_609202	NM_135358
Caenorhabditis elegans	NP_741523	NM_171446
Mus musculus	NP_079718	NM_025442

KEGG BRITE Database

Orthology

K00729

Name

dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117]

References

8076653

Rhea

RHEA:15401

UDP-α-D-glucose

UDP

Enzyme

2.4.1.117

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050570	congenital disorder of glycosylation type I	Alliance of Genome Resources
DOID:0080322	polycystic kidney disease	Alliance of Genome Resources

The Human Phenotype Ontology

Displaying entries **1 - 10** of 29 in total

1

2

3

Next ›

Last »
HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0000010	Recurrent urinary tract infections
HP:0000083	Renal insufficiency
HP:0000105	Enlarged kidney
HP:0000107	Renal cyst
HP:0000790	Hematuria
HP:0000791	Uric acid nephrolithiasis
HP:0000822	Hypertension
HP:0001407	Hepatic cysts
HP:0001634	Mitral valve prolapse

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:620056	polycystic kidney disease 7
ORPHA:730	autosomal dominant polycystic kidney disease

PubChem Disease

MedGen Diseases

Polycystic kidney disease 7

OMIM Phenotypes

POLYCYSTIC KIDNEY DISEASE 7; PKD7

KEGG Diseases

Polycystic kidney disease

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012355
Gene Name: ALG5, dolichyl-phosphate beta-glucosyltransferase

Ortholog

Displaying entries **1 - 10** of 84 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	178822	WB:WBGene00019276
Drosophila melanogaster	34134	FB:FBgn0261020
Latimeria chalumnae	102367426		LATCH07064
Danio rerio	751635	ZFIN:ZDB-GENE-030131-6586	DANRE01379
Ictalurus punctatus	108276693		ICTPU09055
Electrophorus electricus	113572179		ELEEL10800
Salmo trutta	115204641		SALTR80437
Oryzias latipes	101167889		ORYLA04037
Sparus aurata	115594776		SPAAU20799
Xenopus laevis	379570	Xenbase:XB-GENE-946760

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements