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dipeptidyl peptidase 7

Summary

Gene Symbol

DPP7

Organism

Homo sapiens (human)

External Links

NCBI Gene

29952

PubChem

29952

Alliance of Genome Resources

HGNC:14892

Annotation

Keyword

3D-structure
Aminopeptidase
Cleavage on pair of basic residues
Cytoplasmic vesicle
Direct protein sequencing
Glycoprotein
Lysosome
Proteomics identification
Reference proteome
Secreted
Serine protease
Signal
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0ABB0MVF0	Dipeptidyl aminopeptidase II Dipeptidyl peptidase 7 Dipeptidyl peptidase II Quiescent cell proline dipeptidase
Q9UHL4	Dipeptidyl aminopeptidase II Dipeptidyl peptidase 7 Dipeptidyl peptidase II Quiescent cell proline dipeptidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
lysosomal protein catabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

protein metabolic process [inference]

proteolysis

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

protein catabolic process in the vacuole [inference]

lysosomal protein catabolic process

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
Golgi apparatus	IDA
vesicle	IDA	11067927
vesicle	IBA
azurophil granule lumen	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

intracellular organelle lumen [inference]

vacuolar lumen [inference]

azurophil granule lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

azurophil granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

Golgi apparatus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
aminopeptidase activity	IEA
serine-type peptidase activity	TAS	10567372
dipeptidyl-peptidase activity	IBA
serine-type exopeptidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

serine-type peptidase activity

serine-type exopeptidase activity

exopeptidase activity [inference]

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type exopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

serine-type peptidase activity

serine-type exopeptidase activity

exopeptidase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

LYSOSOMAL PRO-X CARBOXYPEPTIDASE

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dipeptidyl-peptidase activity
hydrolase activity
proteolysis
serine-type exopeptidase activity

Displaying **all 3** entries
InterPro
Alpha/Beta hydrolase fold
Peptidase S28
Serine carboxypeptidase S28, SKS domain

Ortholog

Displaying entries **1 - 10** of 56 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	29952	ZFIN:ZDB-GENE-050306-16
Mus musculus	83768	ZFIN:ZDB-GENE-050306-16	MOUSE34426
Rattus norvegicus	83799	ZFIN:ZDB-GENE-050306-16	RATNO25925
Pan troglodytes	473101		PANTR45326
Danio rerio	503737		DANRE36318
Macaca mulatta	721595		MACMU13458
Monodelphis domestica	100022760		MONDO06387
Equus caballus	100059924		HORSE24032
Bos taurus	100125760		BOVIN03523
Pongo abelii	100174214		PONAB35565