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Submissions

ubiquilin 1

Summary

Gene Symbol

UBQLN1

Organism

Homo sapiens (human)

External Links

NCBI Gene

29979

PubChem

29979

Alliance of Genome Resources

HGNC:12508

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Autophagy
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Direct protein sequencing
Endoplasmic reticulum
Nucleus
Phosphoprotein
Proteasome
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UMX0	Protein linking IAP with cytoskeleton 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
regulation of protein ubiquitination	IDA	12634373
positive regulation of ERAD pathway	IMP	18307982
negative regulation of toll-like receptor 3 signaling pathway	IEA
ubiquitin-dependent protein catabolic process	IBA
autophagosome assembly	IBA IMP	20529957

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

aggrephagy

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

aggrephagy

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

aggrephagy

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

ERAD pathway

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

aggrephagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to stress [inference]

response to endoplasmic reticulum stress

ERAD pathway

cellular response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

ERAD pathway

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of post-translational protein modification [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination

positive regulation of protein ubiquitination

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of post-translational protein modification [inference]

positive regulation of protein modification by small protein conjugation or removal [inference]

positive regulation of protein ubiquitination

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of ERAD pathway

positive regulation of cellular process [inference]

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

positive regulation of response to stimulus [inference]

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of transport [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 3 signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

regulation of apoptotic signaling pathway [inference]

regulation of intrinsic apoptotic signaling pathway [inference]

regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytoplasmic pattern recognition receptor signaling pathway [inference]

negative regulation of toll-like receptor 3 signaling pathway

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation transmembrane transport [inference]

negative regulation of calcium ion transmembrane transport [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of ERAD pathway [inference]

positive regulation of ERAD pathway

positive regulation of response to endoplasmic reticulum stress [inference]

positive regulation of ERAD pathway

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

regulation of cation channel activity [inference]

regulation of store-operated calcium channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of calcium ion transmembrane transporter activity [inference]

negative regulation of store-operated calcium channel activity

negative regulation of cation channel activity [inference]

negative regulation of store-operated calcium channel activity

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
cytoplasmic vesicle	IEA
protein-containing complex	IDA
proteasome complex	IEA
plasma membrane	IDA	21143716
aggresome	IDA	16159959 21143716

GO Hierarchy

cellular component

protein-containing complex

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

vacuole [inference]

autophagosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

autophagosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
kinase binding	IPI	11853878
protein binding	IPI	11076969 12095988 15147878 16159959 16189514 16713569 17082820 18199683 18307982 19822669 20059542 21143716 21516116 21988832 22233804 23307288 23459205 25416956 25910212 26871637 29892012 31515488 32296183 32814053 33961781 35914814 36217029
identical protein binding	IPI	16189514 16713569 25416956
polyubiquitin modification-dependent protein binding	IBA IDA	15147878

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

identical protein binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ubiquilin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
polyubiquitin modification-dependent protein binding

Displaying **all 6** entries
InterPro
Heat shock chaperonin-binding
UBA-like superfamily
Ubiquilin
Ubiquitin-associated domain
Ubiquitin-like domain superfamily
Ubiquitin-like domain

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060206	amyotrophic lateral sclerosis type 15	Alliance of Genome Resources
DOID:1289	neurodegenerative disease	Alliance of Genome Resources
DOID:332	amyotrophic lateral sclerosis	Alliance of Genome Resources
DOID:9255	frontotemporal dementia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 70 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32977		FB:FBgn0031057
Mus musculus	56085		MGI:1860276	MOUSE11781
Rattus norvegicus	114590		RGD:620745	RATNO11989
Caenorhabditis elegans	172434		WB:WBGene00008852
Bos taurus	282392			BOVIN34864
Xenopus tropicalis	394829		Xenbase:XB-GENE-986025
Xenopus laevis	446997		Xenbase:XB-GENE-986031
Pan troglodytes	464550	9598_0:0027fb		PANTR44200
Canis lupus familiaris	476312			CANLF00395
Macaca mulatta	713525			MACMU12832

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements