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UDP glucuronosyltransferase family 1 member A8

Summary

Gene Symbol

Ugt1a8

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

301595

KEGG Gene ID

rno:301595

PubChem

301595

Alliance of Genome Resources

RGD:708474

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
M0RB50
A6JQH6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cellular response to organic cyclic compound	IEP	11992647
coumarin catabolic process	IDA	15502008
cellular glucuronidation	IBA
liver development	IBA
steroid metabolic process	ISS

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

secondary metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process [inference]

steroid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

cellular response to organic cyclic compound

cellular response to organic substance [inference]

cellular response to organic cyclic compound

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to organic cyclic compound

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
UDP-glycosyltransferase activity	IEA
enzyme binding	IBA
glucuronosyltransferase activity	IDA TAS	11854153 15502008

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources
DOID:4988	alcoholic pancreatitis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	172085	WB:WBGene00015695
Caenorhabditis elegans	175591	WB:WBGene00010904
Caenorhabditis elegans	178330	WB:WBGene00007455
Drosophila melanogaster	35105	FB:FBgn0032684
Drosophila melanogaster	35137	FB:FBgn0027074
Drosophila melanogaster	35138	FB:FBgn0032713
Drosophila melanogaster	35139	FB:FBgn0027070
Drosophila melanogaster	37420	FB:FBgn0027073
Drosophila melanogaster	40079	FB:FBgn0036842
Drosophila melanogaster	41333	FB:FBgn0026314