GlyCosmos Portal

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Proteomics identification
Reference proteome
Sialic acid
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
F6SGE3
B4DU80
Q969X2	GalNAc alpha-2,6-sialyltransferase VI ST6GalNAc VI Sialyltransferase 7F
A0A0S2Z5G9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
oligosaccharide biosynthetic process	ISS TAS	12668675
glycosylceramide metabolic process	IDA	17123352
cell-cell recognition	IC	12668675
oligosaccharide metabolic process	IBA
glycosphingolipid biosynthetic process	TAS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

amide metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular process [inference]

cell recognition [inference]

cell-cell recognition

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

glycosphingolipid metabolic process

ganglioside metabolic process [inference]

ganglioside biosynthetic process

glycosylceramide metabolic process

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

ganglioside biosynthetic process

ceramide biosynthetic process [inference]

ganglioside biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	ISS
plasma membrane	NAS	10702226
membrane	TAS	10702226
Golgi membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	IBA ISS TAS
protein binding	IPI	16713569 32296183 32814053
sialyltransferase activity	IDA ISS	12668675 17123352

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000160408

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg061

Gene Symbol

ST6GALNAC6

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G79536OW		12668675

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G79536OW		12668675

Displaying **all 2** entries
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G58896AZ		12668675
CMP-Neu5Ac	G00049MO		12668675

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	CAG26710	AJ646881
Mus musculus	NP_058669	NM_016973

KEGG BRITE Database

Orthology

K03376

Name

N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.3.-]

References

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05951		G40183QN	G54733XO
R05959	2.4.3.7	G03277YI	G45714BQ
R05945		G46677TE	G02149VR

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:263	kidney cancer	DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006678
Gene Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103183066		CALMI26272
Danio rerio	407715	ZFIN:ZDB-GENE-060322-7
Astyanax mexicanus	103026356		ASTMX10361
Ictalurus punctatus	108279153		ICTPU11023
Electrophorus electricus	113590038		ELEEL44262
Esox lucius	105015284		ESOLU43407
Salmo trutta	115159920		SALTR71398
Salmo trutta	115203736		SALTR80750
Gadus morhua	115532137		GADMO25336
Poecilia reticulata	103473417		POERE04864

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements