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Repository for lectin-assisted multimodality data
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MIRAGE
major histocompatibility complex, class II, DR beta 1
Summary
- Gene Symbol
-
- HLA-DRB1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Isopeptide bond
- Lysosome
- MHC II
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P01911 |
|
| Q5Y7D1 |
|
| D7RIH8 |
|
| A0A224MM52 |
|
| X5DNQ0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of type II interferon production | ||
| negative regulation of T cell proliferation | ||
| positive regulation of kinase activity | ||
| positive regulation of T cell activation | ||
| positive regulation of ERK1 and ERK2 cascade |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| lumenal side of endoplasmic reticulum membrane | ||
| external side of plasma membrane | ||
| extracellular exosome | ||
| trans-Golgi network membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| MHC class II protein complex binding | ||
| polysaccharide binding | ||
| peptide antigen binding | ||
| protein binding | ||
| T cell receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12859 | choreatic disease | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:12918 | thromboangiitis obliterans | |
| DOID:13025 | retinopathy of prematurity | |
| DOID:13141 | uveitis | |
| DOID:13166 | allergic bronchopulmonary aspergillosis | |
| DOID:13241 | Behcet's disease | |
| DOID:13258 | typhoid fever | |
| DOID:13375 | temporal arteritis | |
| DOID:1340 | pure red-cell aplasia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14969 | MGI:95901 | MOUSE20174 | ||
| 24981 | RGD:1595922 | |||
| 30762 | ZFIN:ZDB-GENE-980526-200 | DANRE42489 | ||
| 294270 | RGD:1593282 | RATNO21721 | ||
| 368615 | ZFIN:ZDB-GENE-030616-319 | DANRE43735 | ||
| 368703 | ZFIN:ZDB-GENE-030616-99 | DANRE42448 | ||
| 368877 | DANRE42489 | |||
| 381091 | MGI:95902 | |||
| 462594 | PANTR37841 | |||
| 474860 | CANLF02603 |
