GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
transcription coactivator binding	IPI	27956576
protein serine/threonine kinase activity	ISO
JUN kinase kinase kinase activity	IEA
MAP kinase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

histone modifying activity [inference]

histone kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

type II transforming growth factor beta receptor binding

receptor tyrosine kinase binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription coactivator binding

DNA-binding transcription factor binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein serine/threonine kinase binding

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ubiquitin-like protein binding [inference]

ubiquitin binding [inference]

linear polyubiquitin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mitogen-activated protein kinase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
JNK cascade
immune response
kinase activity
magnesium ion binding
nucleotide binding
phosphorylation
positive regulation of canonical NF-kappaB signal transduction
transferase activity

Displaying **all 7** entries
InterPro
Mitogen-activated protein (MAP) kinase kinase kinase 7-like
Mitogen-activated protein kinase kinase kinase 7
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2349	arteriosclerosis	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 80** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Salarias fasciatus	115402005	SALFA05249
Gadus morhua	115534484	GADMO32513
Sparus aurata	115574139	SPAAU61015
Strigops habroptila	115609308	STRHB16925
Corvus moneduloides	116442258	CORMO17881
Chelonoidis abingdonii	116820302	CHEAB25644
Rhinolophus ferrumequinum	117020162	RHIFE10602
Scophthalmus maximus	118289714	SCOMX17075
Balaenoptera musculus	118905068	BALMU27411
Panthera leo	122220179	PANLE16219

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Acknowledgements