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Palmitoyl-protein thioesterase 1

Summary
Gene Symbol
  • Ppt1
Organism
Drosophila melanogaster (fruit fly)
NCBI Gene
31805
PubChem
31805
Alliance of Genome Resources
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Lysosome
  • Proteomics identification
  • Reference proteome
  • Signal
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
S5WMX5
  • Palmitoyl-protein hydrolase 1
Q9W3C7
  • Palmitoyl-protein hydrolase 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
endocytosis
endocytosis
receptor-mediated endocytosis
nervous system development
determination of adult lifespan
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
palmitoyl-protein thioesterase
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
hydrolase activity
macromolecule depalmitoylation
nervous system development
palmitoyl hydrolase activity
palmitoyl-(protein) hydrolase activity
receptor-mediated endocytosis
Displaying all 2 entries
InterPro
Alpha/Beta hydrolase fold
Palmitoyl protein thioesterase
Alliance of Genome Resources
Expression
Displaying all 2 entries
Location References
Rhea

RHEA:19233

H2O
H+ + hexadecanoate
Enzyme
PMID
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0110721 neuronal ceroid lipofuscinosis 1
DOID:14503 neuronal ceroid lipofuscinosis
Ortholog
Displaying all 5 entries
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5538 Xenbase:XB-GENE-923070
19063 Xenbase:XB-GENE-923070
29411 Xenbase:XB-GENE-923070
31805 Xenbase:XB-GENE-923070
191744 Xenbase:XB-GENE-923070
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025