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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
heterogeneous nuclear ribonucleoprotein A2/B1
Summary
- Gene Symbol
-
- HNRNPA2B1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Host-virus interaction
- Isopeptide bond
- Methylation
- Nucleus
- Phosphoprotein
- RNA-binding
- Reference proteome
- Repeat
- Ribonucleoprotein
- Secreted
- Spliceosome
- Ubl conjugation
- mRNA transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P22626 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of mRNA splicing, via spliceosome | ||
| mRNA transport | ||
| primary miRNA processing | ||
| mRNA export from nucleus | ||
| mRNA splicing, via spliceosome |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| spliceosomal complex | ||
| membrane | ||
| ribonucleoprotein complex | ||
| chromosome, telomeric region | ||
| Cajal body |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| N6-methyladenosine-containing RNA reader activity | ||
| mRNA 3'-UTR binding | ||
| pre-mRNA intronic binding | ||
| G-rich strand telomeric DNA binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Heterogeneous nuclear ribonucleoprotein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| InterPro |
|---|
| Nucleotide-binding alpha-beta plait domain superfamily |
| RNA recognition motif domain |
| RNA-binding domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050881 | inclusion body myopathy with Paget disease of bone and frontotemporal dementia | |
| DOID:0111384 | inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 2 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1289 | neurodegenerative disease | |
| DOID:224 | transient cerebral ischemia | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:423 | myopathy | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:7148 | rheumatoid arthritis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 43385 | FB:FBgn0001215 | |||
| 48535 | FB:FBgn0004237 | |||
| 53379 | MGI:104819 | MOUSE48822 | ||
| 177101 | WB:WBGene00001999 | |||
| 362361 | RGD:1310403 | RATNO31836 | ||
| 379158 | Xenbase:XB-GENE-17340471 | |||
| 380082 | Xenbase:XB-GENE-490997 | |||
| 463299 | 9598_0:001fc0 | PANTR39870 | ||
| 475260 | CANLF03757 | |||
| 507564 | BOVIN28161 |
