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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
haptoglobin
Summary
- Gene Symbol
-
- HP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Alternative splicing
- Antibiotic
- Antioxidant
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hemoglobin-binding
- Immunity
- Proteomics identification
- Reference proteome
- Repeat
- Secreted
- Serine protease homolog
- Signal
- Sushi
- Proteins
| UniProt | Protein Name |
|---|---|
| P00738 |
|
| Q6PEJ8 |
|
| A0A0C4DGL8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| defense response | ||
| cellular oxidant detoxification | ||
| zymogen activation |
|
|
| immune system process | ||
| defense response to bacterium |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| haptoglobin-hemoglobin complex | ||
| specific granule lumen | ||
| tertiary granule lumen | ||
| endocytic vesicle lumen | ||
| extracellular region |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| hemoglobin binding | ||
| antioxidant activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Trypsin
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| proteolysis |
| serine-type endopeptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12241 | beta thalassemia | |
| DOID:12554 | hemolytic-uremic syndrome | |
| DOID:1287 | cardiovascular system disease | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:13189 | gout | |
| DOID:1324 | lung cancer | |
| DOID:13378 | Kawasaki disease | |
| DOID:13580 | cholestasis | |
| DOID:14067 | Plasmodium falciparum malaria | |
| DOID:1936 | atherosclerosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 15439 | MGI:96211 | MOUSE57964 | ||
| 24464 | RGD:2825 | RATNO14957 | ||
| 280692 | BOVIN10728 | |||
| 397061 | PIGXX27148 | |||
| 454233 | 9598_0:0042ca | |||
| 479668 | CANLF15993 | |||
| 566096 | ZFIN:ZDB-GENE-030131-1259 | DANRE41173 | ||
| 706936 | MACMU26470 | |||
| 709274 | MACMU26456 | |||
| 745555 | 9598_0:004319 |
