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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
haptoglobin
Summary
- Gene Symbol
-
- HP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Alternative splicing
- Antibiotic
- Antioxidant
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hemoglobin-binding
- Immunity
- Proteomics identification
- Reference proteome
- Repeat
- Secreted
- Serine protease homolog
- Signal
- Sushi
- Proteins
| UniProt | Protein Name |
|---|---|
| P00738 |
|
| Q6PEJ8 |
|
| A0A0C4DGL8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| defense response | ||
| cellular oxidant detoxification | ||
| zymogen activation |
|
|
| immune system process | ||
| defense response to bacterium |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| haptoglobin-hemoglobin complex | ||
| specific granule lumen | ||
| tertiary granule lumen | ||
| endocytic vesicle lumen | ||
| extracellular region |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| hemoglobin binding | ||
| antioxidant activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Trypsin
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| proteolysis |
| serine-type endopeptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:583 | hemolytic anemia | |
| DOID:5844 | myocardial infarction | |
| DOID:6000 | congestive heart failure | |
| DOID:6432 | pulmonary hypertension | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:784 | chronic kidney disease | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9477 | pulmonary embolism | |
| DOID:9744 | type 1 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 107561453 | SINGR50092 | |||
| 108270509 | ICTPU00902 | |||
| 109310761 | CROPO16742 | |||
| 110192397 | PHACI19412 | |||
| 112929485 | VULVU24606 | |||
| 113577819 | ELEEL02048 | |||
| 115041172 | ECHNA23538 | |||
| 115167366 | SALTR83076 | |||
| 115182862 | SALTR50412 | |||
| 115186339 | SALTR46465 |
