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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paralytic
Summary
- Gene Symbol
-
- para
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coiled coil
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- RNA editing
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Voltage-gated channel
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sensory perception of sound | ||
| regulation of postsynaptic membrane potential | ||
| sodium ion transport | ||
| mechanosensory behavior | ||
| membrane depolarization during action potential |
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| sodium channel activity | ||
| calcium ion binding | ||
| monoatomic cation channel activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium channel alpha subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ion transport domain |
| Voltage-dependent channel domain superfamily |
| Voltage-gated cation channel calcium and sodium |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080422 | Dravet syndrome | |
| DOID:0080445 | developmental and epileptic encephalopathy 13 | |
| DOID:0081116 | benign familial infantile seizures 3 | |
| DOID:0081118 | benign familial infantile seizures 5 | |
| DOID:0081354 | congenital myopathy 22A | |
| DOID:0081355 | congenital myopathy 22B | |
| DOID:0081424 | familial focal epilepsy with variable foci 4 | |
| DOID:0110218 | Brugada syndrome 1 | |
| DOID:0110433 | dilated cardiomyopathy 1E | |
| DOID:0110646 | long QT syndrome 3 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4814623 | 7237_0:0009a5 | |||
| 6524977 | 7245_1:000693 | |||
| 6550490 | 7220_1:0030ae | |||
| 6565802 | 7222_1:002e9c | |||
| 6585204 | 7230_1:000477 | |||
| 6603964 | 7234_1:00261c | |||
| 6617946 | 7238_0:002acb | |||
| 6631799 | 7244_1:0004fb | |||
| 6649183 | 7260_0:002876 | |||
| 6726141 | 7240_1:002fa8 |
