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paralytic
Summary
- Gene Symbol
-
- para
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coiled coil
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- RNA editing
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Voltage-gated channel
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sensory perception of sound | ||
| regulation of postsynaptic membrane potential | ||
| sodium ion transport | ||
| mechanosensory behavior | ||
| membrane depolarization during action potential |
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| sodium channel activity | ||
| calcium ion binding | ||
| monoatomic cation channel activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium channel alpha subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ion transport domain |
| Voltage-dependent channel domain superfamily |
| Voltage-gated cation channel calcium and sodium |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080422 | Dravet syndrome | |
| DOID:0080445 | developmental and epileptic encephalopathy 13 | |
| DOID:0081116 | benign familial infantile seizures 3 | |
| DOID:0081118 | benign familial infantile seizures 5 | |
| DOID:0081354 | congenital myopathy 22A | |
| DOID:0081355 | congenital myopathy 22B | |
| DOID:0081424 | familial focal epilepsy with variable foci 4 | |
| DOID:0110218 | Brugada syndrome 1 | |
| DOID:0110433 | dilated cardiomyopathy 1E | |
| DOID:0110646 | long QT syndrome 3 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100125099 | Xenbase:XB-GENE-5812330 | |||
| 100485924 | Xenbase:XB-GENE-6037407 | |||
| 100486750 | Xenbase:XB-GENE-6447552 | |||
| 100488621 | Xenbase:XB-GENE-978019 | |||
| 100492371 | Xenbase:XB-GENE-982767 | |||
| 108011109 | 28584_1:00380c | |||
| 108032991 | 125945_1:000469 | |||
| 108040189 | 1041015_1:002f23 | |||
| 108059094 | 29030_1:0002cd | |||
| 108079940 | 30033_0:001fe9 |
