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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paralytic
Summary
- Gene Symbol
-
- para
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coiled coil
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- RNA editing
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Voltage-gated channel
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sensory perception of sound | ||
| regulation of postsynaptic membrane potential | ||
| sodium ion transport | ||
| mechanosensory behavior | ||
| membrane depolarization during action potential |
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| sodium channel activity | ||
| calcium ion binding | ||
| monoatomic cation channel activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium channel alpha subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ion transport domain |
| Voltage-dependent channel domain superfamily |
| Voltage-gated cation channel calcium and sodium |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080422 | Dravet syndrome | |
| DOID:0080445 | developmental and epileptic encephalopathy 13 | |
| DOID:0081116 | benign familial infantile seizures 3 | |
| DOID:0081118 | benign familial infantile seizures 5 | |
| DOID:0081354 | congenital myopathy 22A | |
| DOID:0081355 | congenital myopathy 22B | |
| DOID:0081424 | familial focal epilepsy with variable foci 4 | |
| DOID:0110218 | Brugada syndrome 1 | |
| DOID:0110433 | dilated cardiomyopathy 1E | |
| DOID:0110646 | long QT syndrome 3 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 111596842 | 7224_1:001ab2 | |||
| 115765171 | 47314_0:00213f | |||
| 116654462 | 7217_1:003279 | |||
| 117146522 | 7226_0:0031aa | |||
| 117578157 | 7291_1:0007ff | |||
| 117581312 | 7266_1:001242 | |||
| 117782864 | 198719_0:000181 | |||
| 117903527 | 7241_1:000328 | |||
| 119556356 | 1486046_0:0001fc | |||
| 120457181 | 129105_0:00325a |
