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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paralytic
Summary
- Gene Symbol
-
- para
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Coiled coil
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- RNA editing
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Voltage-gated channel
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sensory perception of sound | ||
| regulation of postsynaptic membrane potential | ||
| sodium ion transport | ||
| mechanosensory behavior | ||
| membrane depolarization during action potential |
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel complex | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated sodium channel activity | ||
| sodium channel activity | ||
| calcium ion binding | ||
| monoatomic cation channel activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- sodium channel alpha subunit
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ion transport domain |
| Voltage-dependent channel domain superfamily |
| Voltage-gated cation channel calcium and sodium |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110682 | congenital myasthenic syndrome 16 | |
| DOID:0111074 | progressive familial heart block type IA | |
| DOID:0111183 | familial hemiplegic migraine 3 | |
| DOID:0111294 | generalized epilepsy with febrile seizures plus 2 | |
| DOID:0111537 | paroxysmal extreme pain disorder | |
| DOID:0111538 | paramyotonia congenita of Von Eulenburg | |
| DOID:0111730 | familial episodic pain syndrome 2 | |
| DOID:0111731 | familial episodic pain syndrome 3 | |
| DOID:11446 | sciatic neuropathy | |
| DOID:13884 | sick sinus syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6323 | HGNC:10585 | |||
| 6326 | HGNC:10588 | |||
| 6328 | HGNC:10590 | |||
| 6329 | HGNC:10591 | |||
| 6331 | HGNC:10593 | |||
| 6332 | HGNC:10594 | |||
| 6334 | HGNC:10596 | |||
| 6335 | HGNC:10597 | |||
| 6336 | HGNC:10582 | |||
| 11280 | HGNC:10583 |
