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Guidelines

MIRAGE

ArfGAP with FG repeats 1

Summary

Gene Symbol

AGFG1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3267

PubChem

3267

Alliance of Genome Resources

HGNC:5175

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasmic vesicle
DNA-binding
Developmental protein
Glycoprotein
Nucleus
Phosphoprotein
Reference proteome
Repeat
Spermatogenesis
Zinc-finger
mRNA transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0S2Z444
P52594	HIV-1 Rev-binding protein Nucleoporin-like protein RIP Rev-interacting protein Rev/Rex activation domain-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
acrosome assembly	IBA
mRNA export from nucleus	TAS	7634337
spermatid nucleus differentiation	IBA
intermediate filament organization	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

spermatid nucleus differentiation

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

vesicle organization [inference]

secretory granule organization [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

supramolecular fiber organization [inference]

intermediate filament organization

reproductive process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

cellular process involved in reproduction in multicellular organism [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nuclear pore	TAS	7637788
cytoplasm	IBA
cytosol	TAS
cytoplasmic vesicle	IBA
intracellular membrane-bounded organelle	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

nuclear pore

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA binding	IEA
RNA binding	TAS	7634337
GTPase activator activity	IEA
protein binding	IPI	11545741 18775314 25416956
zinc ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Arf-gap domain and fg repeat-containing protein

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
ARFGAP/RecO-like zinc finger
Arf GTPase activating protein
ArfGAP domain superfamily

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3267	Xenbase:XB-GENE-5750510
Drosophila melanogaster	3268	FB:FBgn0020304
Mus musculus	15463	Xenbase:XB-GENE-5750510	MOUSE27646
Drosophila melanogaster	231801	FB:FBgn0020304
Danio rerio	327597		DANRE09297
Xenopus tropicalis	363266	Xenbase:XB-GENE-5750510
Pan troglodytes	459990		PANTR29925
Macaca mulatta	708910		MACMU06401
Monodelphis domestica	100014819		MONDO32596
Taeniopygia guttata	100217620		TAEGU30411

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Last updated: April 7, 2025