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hydroxysteroid 17-beta dehydrogenase 4

Summary

Gene Symbol

HSD17B4

Aliases

17-beta-HSD IV
17-beta-hydroxysteroid dehydrogenase 4
17beta-estradiol dehydrogenase type IV
3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase
D-3-hydroxyacyl-CoA dehydratase
D-bifunctional protein, peroxisomal
DBP
MFE-2
SDR8C1
beta-hydroxyacyl dehydrogenase
beta-keto-reductase
peroxisomal multifunctional protein 2
short chain dehydrogenase/reductase family 8C, member 1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3295

HGNC

5213

KEGG Gene ID

hsa:3295

PubChem

3295

Alliance of Genome Resources

HGNC:5213

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Deafness
Direct protein sequencing
Disease variant
Fatty acid metabolism
Isomerase
Lipid metabolism
Lyase
NAD
Oxidoreductase
Peroxisome
Phosphoprotein
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B3KSP2
P51659	17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein Multifunctional protein 2 Short chain dehydrogenase/reductase family 8C member 1
B2R659
A0A0S2Z4J1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
Sertoli cell development	IEA
osteoblast differentiation	HDA	16210410
very long-chain fatty acid metabolic process	IEA
fatty acid beta-oxidation	IBA IDA IEA	10400999 10706581 15060085 9482850
medium-chain fatty-acyl-CoA metabolic process	IDA	9089413

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

hormone metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid derivative metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

lipid metabolic process [inference]

steroid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid derivative metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

steroid metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process

fatty acid catabolic process [inference]

fatty acid beta-oxidation

fatty acid oxidation [inference]

fatty acid beta-oxidation

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation [inference]

fatty acid beta-oxidation

cellular lipid catabolic process [inference]

fatty acid catabolic process [inference]

fatty acid beta-oxidation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

reproductive process [inference]

developmental process involved in reproduction [inference]

Sertoli cell development

developmental process [inference]

developmental process involved in reproduction [inference]

Sertoli cell development

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytosol
membrane	HDA	16210410
peroxisome	IBA IDA NAS	15599942 7487879 9482850
peroxisomal membrane	HDA	21525035
peroxisomal matrix

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

microbody lumen [inference]

peroxisomal matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

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GO Term	Evidence Code	PMID
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	IEA
3-hydroxyacyl-CoA dehydratase activity	IDA	10400999 9089413 9482850
17-beta-hydroxysteroid dehydrogenase (NAD+) activity	IBA
protein homodimerization activity	IDA	15644212 9089413
estradiol 17-beta-dehydrogenase [NAD(P)] activity	IDA	7487879

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-hydroxyacyl-CoA dehydrogenase activity

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity

lyase activity [inference]

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

enoyl-CoA hydratase activity

3-hydroxyacyl-CoA dehydratase activity

3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity

isomerase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000133835

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K12405

Name

(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]

References

Disease

Disease Ontology

Displaying entries **1 - 10** of **121** in total

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DO ID	Disease Name	Source
DOID:0050444	infantile Refsum disease	DisGeNET
DOID:0050562	West syndrome	DisGeNET
DOID:0050753	cerebellar ataxia	DisGeNET
DOID:0050857	Perrault syndrome	DisGeNET DisGeNET Alliance of Genome Resources
DOID:0050951	hereditary ataxia	DisGeNET
DOID:0060249	scoliosis	DisGeNET
DOID:0060602	alpha-methylacyl-CoA racemase deficiency	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0080348	Alzheimer's disease 1	DisGeNET
DOID:0080476	peroxisome biogenesis disorder 1A	DisGeNET

The Human Phenotype Ontology

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000107	Renal cyst
HP:0000133	Gonadal dysgenesis
HP:0000218	High palate
HP:0000239	Large fontanelles
HP:0000256	Macrocephaly
HP:0000268	Dolichocephaly
HP:0000270	Delayed cranial suture closure
HP:0000278	Retrognathia
HP:0000286	Epicanthus

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:261515	d-bifunctional protein deficiency
OMIM:233400	Perrault syndrome 1

PubChem Disease

GHR Health Conditions

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000062
Gene Name: hydroxysteroid (17-beta) dehydrogenase 4

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	174181	WB:WBGene00017123
Caenorhabditis elegans	180950	WB:WBGene00000991
Drosophila melanogaster	32582	FB:FBgn0030731
Ciona intestinalis	100187421		CIOIN13368
Callorhinchus milii	103181119		CALMI21985
Latimeria chalumnae	102356548		LATCH02922
Danio rerio	393105	ZFIN:ZDB-GENE-040421-1	DANRE43883
Ictalurus punctatus	108265438		ICTPU29751
Electrophorus electricus	113571049		ELEEL07837
Salmo salar	106585849		SALSA110209

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements