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heat shock transcription factor 1
Summary
- Gene Symbol
-
- HSF1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Centromere
- Chromosome
- Cytoskeleton
- DNA repair
- DNA-binding
- Direct protein sequencing
- Host-virus interaction
- Isopeptide bond
- Kinetochore
- Nucleus
- Phosphoprotein
- Reference proteome
- Stress response
- Transcription regulation
- Ubl conjugation
- mRNA processing
- mRNA transport
- Proteins
| UniProt | Protein Name |
|---|---|
| Q00613 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of apoptotic DNA fragmentation | ||
| cellular response to L-glutamine | ||
| positive regulation of DNA-binding transcription factor activity | ||
| cellular response to angiotensin | ||
| cellular response to sodium arsenite |
GO Hierarchy
- response to activity
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of DNA metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| heterochromatin | ||
| euchromatin | ||
| ribonucleoprotein complex | ||
| mitotic spindle pole | ||
| PML body |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | ||
| protein binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA binding | ||
| Hsp90 protein binding |
GO Hierarchy
molecular function
binding [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Heat shock factor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:11383 | cryptorchidism | |
| DOID:12858 | Huntington's disease | |
| DOID:14330 | Parkinson's disease | |
| DOID:224 | transient cerebral ischemia | |
| DOID:6000 | congestive heart failure | |
| DOID:767 | muscular atrophy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 15499 | MGI:96238 | MOUSE16427 | ||
| 37068 | FB:FBgn0001222 | |||
| 58123 | ZFIN:ZDB-GENE-000616-16 | DANRE15579 | ||
| 79245 | RGD:620913 | RATNO37407 | ||
| 173078 | WB:WBGene00002004 | |||
| 475124 | CANLF03310 | |||
| 714078 | MACMU44550 | |||
| 741396 | 9598_0:00247d | PANTR43470 | ||
| 779172 | Xenbase:XB-GENE-997146 | |||
| 852806 | SGD:S000003041 |
