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domeless

Summary

Gene Symbol

dome

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

32976

PubChem

32976

Alliance of Genome Resources

FB:FBgn0043903

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VWE0	Protein domeless

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
wing disc morphogenesis	IMP	28045022
locomotor rhythm	IMP	22305007
compound eye morphogenesis	IMP	15170700
cytokine-mediated signaling pathway	IGI	16277982
receptor signaling pathway via JAK-STAT	IDA IGI IMP	11696329 11825879 16094372 17855388 19520911 20841381 26658615 31072879 32917740 35905720

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

cellular process involved in reproduction in multicellular organism [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

long-term memory

pattern specification process [inference]

regionalization [inference]

segmentation [inference]

blastoderm segmentation

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

determination of digestive tract left/right asymmetry

embryonic pattern specification [inference]

blastoderm segmentation

behavior [inference]

learning or memory [inference]

memory [inference]

long-term memory

rhythmic behavior [inference]

circadian behavior [inference]

locomotor rhythm

locomotory behavior [inference]

locomotor rhythm

developmental process [inference]

anatomical structure morphogenesis [inference]

hindgut morphogenesis

animal organ morphogenesis [inference]

imaginal disc morphogenesis [inference]

wing disc morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

compound eye morphogenesis

anatomical structure development [inference]

regeneration [inference]

tissue regeneration

system development [inference]

respiratory system development [inference]

open tracheal system development

growth [inference]

developmental growth [inference]

tissue regeneration

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

locomotor rhythm

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
apicolateral plasma membrane
apical plasma membrane	IDA	12403714 18424141
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	25923769
protein tyrosine kinase binding	IPI	26658615
cytokine receptor activity	IDA IGI	11696329 16277982 17855388 32917740
STAT family protein binding	IPI	26658615
protein heterodimerization activity	IPI	20689801 26658615

GO Hierarchy

molecular function

binding [inference]

protein binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

STAT family protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

protein dimerization activity [inference]

protein heterodimerization activity

SOCS family protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 3** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
nucleus	PMID:12586061
membrane	FB:FBrf0231198
apical plasma membrane	PMID:12403714 PMID:18424141

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080269	autosomal dominant nonsyndromic deafness 73	Alliance of Genome Resources
DOID:0110529	autosomal recessive nonsyndromic deafness 84A	Alliance of Genome Resources
DOID:934	viral infectious disease	Alliance of Genome Resources

Ortholog

Displaying entry **41 - 41** of 41 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila gunungcola	128264191	103775_0:00307b

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements