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solute carrier family 5 (sodium-dependent vitamin transporter), member 6

Summary

Gene Symbol

Slc5a6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

330064

PubChem

330064

Alliance of Genome Resources

MGI:2660847

Annotation

Keyword

Biotin
Cell membrane
Glycoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TY45
Q5U4D8	Solute carrier family 5 member 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
biotin metabolic process	IMP	23104561
sodium ion transport	IBA
biotin import across plasma membrane	ISO ISS
pantothenate transmembrane transport	IBA IMP ISO ISS	23104561
biotin transport	IBA ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

biotin metabolic process

organonitrogen compound metabolic process [inference]

biotin metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

biotin metabolic process

sulfur compound metabolic process [inference]

biotin metabolic process

heterocycle metabolic process [inference]

biotin metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

biotin metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

biotin metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

biotin metabolic process

organic cyclic compound metabolic process [inference]

biotin metabolic process

organonitrogen compound metabolic process [inference]

biotin metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

biotin metabolic process

sulfur compound metabolic process [inference]

biotin metabolic process

heterocycle metabolic process [inference]

biotin metabolic process

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vitamin transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

iodide transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transport [inference]

iodide transport [inference]

iodide transmembrane transport

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vascular transport [inference]

transport across blood-brain barrier

inorganic anion transport [inference]

iodide transport [inference]

iodide transmembrane transport

inorganic anion transmembrane transport [inference]

iodide transmembrane transport

vitamin transport [inference]

biotin transport

biotin import across plasma membrane

vitamin transmembrane transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

monoatomic anion transmembrane transport [inference]

iodide transmembrane transport

vitamin transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

iodide transmembrane transport

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

biotin import across plasma membrane

pantothenate transmembrane transport

carboxylic acid transmembrane transport [inference]

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

biotin import across plasma membrane

pantothenate transmembrane transport

carboxylic acid transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

modified amino acid transport [inference]

pantothenate transmembrane transport

nitrogen compound transport [inference]

amide transport [inference]

biotin transport

biotin import across plasma membrane

pantothenate transmembrane transport

modified amino acid transport [inference]

pantothenate transmembrane transport

sulfur compound transport [inference]

biotin transport

biotin import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

biotin import across plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
apical plasma membrane	ISO ISS
plasma membrane	IMP ISO ISS	21183659 23104561
brush border membrane	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
monocarboxylate:sodium symporter activity	IMP	23104561
amide transmembrane transporter activity	IMP	23104561
sodium-dependent multivitamin transmembrane transporter activity	IBA IMP ISO	23104561
pantothenate transmembrane transporter activity	IMP ISO	23104561
iodide transmembrane transporter activity	ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

biotin transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

biotin transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

monoatomic anion transmembrane transporter activity [inference]

iodide transmembrane transporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

iodide transmembrane transporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

amide transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

vitamin transmembrane transporter activity

sulfur compound transmembrane transporter activity

biotin transmembrane transporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

sodium-dependent multivitamin transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

sodium-dependent multivitamin transporter

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
biotin transport
pantothenate transmembrane transport
salt transmembrane transporter activity
sodium-dependent multivitamin transmembrane transporter activity

Displaying **all 3** entries
InterPro
Sodium/glucose symporter superfamily
Sodium/solute symporter, conserved site
Sodium/solute symporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050718	vitamin metabolic disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **116** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8884		HGNC:11041	HUMAN61918
Drosophila melanogaster	37294		FB:FBgn0034494
Rattus norvegicus	170551	10116_1:00250c	RGD:69648	RATNO35859
Caenorhabditis elegans	178127		WB:WBGene00014092
Drosophila melanogaster	326229		FB:FBgn0052669
Pan troglodytes	459096			PANTR27257
Canis lupus familiaris	475698			CANLF04976
Bos taurus	516021			BOVIN02800
Danio rerio	563356		ZFIN:ZDB-GENE-041001-177	DANRE20002
Macaca mulatta	699074			MACMU07449

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements