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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dopamine 2-like receptor
Summary
- Gene Symbol
-
- Dop2R
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8IS44 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| anesthesia-resistant memory | ||
| positive regulation of MAPK cascade | ||
| dopamine receptor signaling pathway | ||
| G protein-coupled receptor signaling pathway | ||
| adenylate cyclase-activating adrenergic receptor signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled amine receptor activity | ||
| G protein-coupled receptor activity | ||
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- dopamine D2-like receptor
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050425 | restless legs syndrome | |
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:0080855 | Parkinsonism | |
| DOID:0081292 | traumatic brain injury | |
| DOID:0111428 | essential tremor 1 | |
| DOID:10024 | migraine with aura | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 108105013 | 29029_1:001932 | |||
| 108133968 | 42026_0:000c0f | |||
| 108147604 | 30023_1:00071e | |||
| 108164954 | 7229_0:002a75 | |||
| 108607218 | 30019_1:002929 | |||
| 108618372 | 7263_1:002b61 | |||
| 110184171 | 7274_0:00221c | |||
| 111078843 | 7282_1:002836 | |||
| 111602821 | 7224_1:001cef | |||
| 115565439 | 7232_1:003100 |
