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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paraoxonase 2
Summary
- Gene Symbol
-
- Pon2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Disulfide bond
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Reference proteome
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q62086 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to toxic substance | ||
| lactone catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| identical protein binding |
|
|
| arylesterase activity | ||
| acyl-L-homoserine-lactone lactonohydrolase activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serum paraoxonase/arylesterase 2
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
| Gene Ontology |
|---|
| acyl-L-homoserine-lactone lactonohydrolase activity |
| arylesterase activity |
| hydrolase activity |
| metal ion binding |
| response to toxic substance |
| InterPro |
|---|
| Arylesterase |
| Paraoxonase2 |
| Six-bladed beta-propeller, TolB-like |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1289 | neurodegenerative disease | |
| DOID:13810 | familial hypercholesterolemia | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:3393 | coronary artery disease | |
| DOID:3526 | cerebral infarction | |
| DOID:8725 | vascular dementia | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100340152 | RABIT01663 | |||
| 100407939 | CALJA43679 | |||
| 100437018 | PONAB32942 | |||
| 100466658 | AILME13081 | |||
| 100551677 | ANOCA08054 | |||
| 100603799 | NOMLE02943 | |||
| 100667197 | LOXAF17690 | |||
| 100721821 | 10141_0:0039fc | CAVPO06117 | ||
| 100762539 | 10029_0:00033c | CRIGR15699 | ||
| 100972315 | PANPA36667 |
