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apolipoprotein A4

Summary

Gene Symbol

APOA4

Organism

Homo sapiens (human)

External Links

NCBI Gene

337

PubChem

337

Alliance of Genome Resources

HGNC:602

Annotation

Keyword

3D-structure
Chylomicron
HDL
Lipid transport
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P06727	Apolipoprotein A4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 31 in total

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GO Term	Evidence Code	PMID
response to triglyceride	IEA
lipoprotein metabolic process	IEA
protein-lipid complex assembly	IMP	16159879
lipid homeostasis	IDA	3095477
positive regulation of CoA-transferase activity	IDA	1935934

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

innate immune response [inference]

innate immune response in mucosa

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

phosphatidylcholine metabolic process

catabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

organic substance catabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

cellular catabolic process [inference]

hydrogen peroxide catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

lipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

protein metabolic process [inference]

lipoprotein metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

lipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

phosphatidylcholine metabolic process

organic substance catabolic process [inference]

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

cellular catabolic process [inference]

hydrogen peroxide catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly

plasma lipoprotein particle assembly [inference]

chylomicron assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

axon development [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-containing complex assembly [inference]

protein-lipid complex assembly

plasma lipoprotein particle assembly [inference]

chylomicron assembly

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-lipid complex assembly

plasma lipoprotein particle assembly [inference]

chylomicron assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle assembly [inference]

chylomicron assembly

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

triglyceride-rich lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle assembly [inference]

chylomicron assembly

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis

acylglycerol homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to oxidative stress [inference]

response to hydroperoxide [inference]

response to lipid hydroperoxide

response to wounding [inference]

response to axon injury [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

innate immune response [inference]

innate immune response in mucosa

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to stilbenoid

response to lipid [inference]

response to oxygen-containing compound [inference]

response to hydroperoxide [inference]

response to lipid hydroperoxide

response to triglyceride

cellular response to stimulus [inference]

cellular response to stress [inference]

neuron projection regeneration [inference]

axon regeneration [inference]

peripheral nervous system axon regeneration

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

phospholipid transport [inference]

phospholipid efflux

sterol transport [inference]

cholesterol transport [inference]

organophosphate ester transport [inference]

phospholipid transport [inference]

phospholipid efflux

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of cellular catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of lipid catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of triglyceride metabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of lipid biosynthetic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of lipid catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of triglyceride metabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of intestinal cholesterol absorption

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption

regulation of intestinal absorption [inference]

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption

regulation of lipid localization [inference]

regulation of lipid transport [inference]

regulation of sterol transport [inference]

regulation of cholesterol transport

regulation of intestinal cholesterol absorption

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of lipid catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of small molecule metabolic process [inference]

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of plasma lipoprotein oxidation

negative regulation of multicellular organismal process [inference]

negative regulation of plasma lipoprotein oxidation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of cellular biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of fatty acid biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

regulation of cellular catabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

regulation of triglyceride metabolic process [inference]

regulation of triglyceride catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of cellular catabolic process [inference]

positive regulation of triglyceride catabolic process

positive regulation of fatty acid metabolic process [inference]

positive regulation of fatty acid biosynthetic process

positive regulation of triglyceride metabolic process [inference]

positive regulation of triglyceride catabolic process

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of plasma lipoprotein oxidation

regulation of cellular component organization [inference]

regulation of plasma lipoprotein oxidation [inference]

negative regulation of plasma lipoprotein oxidation

negative regulation of cellular component organization [inference]

negative regulation of plasma lipoprotein oxidation

regulation of multicellular organismal process [inference]

regulation of plasma lipoprotein oxidation [inference]

negative regulation of plasma lipoprotein oxidation

regulation of system process [inference]

regulation of digestive system process [inference]

regulation of intestinal absorption [inference]

regulation of intestinal lipid absorption [inference]

regulation of intestinal cholesterol absorption

negative regulation of multicellular organismal process [inference]

negative regulation of plasma lipoprotein oxidation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of triglyceride lipase activity [inference]

positive regulation of lipoprotein lipase activity

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of triglyceride lipase activity [inference]

positive regulation of lipoprotein lipase activity

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of hydrolase activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of lipase activity [inference]

positive regulation of triglyceride lipase activity [inference]

positive regulation of lipoprotein lipase activity

regulation of lipase activity [inference]

regulation of lipoprotein lipase activity [inference]

positive regulation of lipoprotein lipase activity

positive regulation of lipase activity [inference]

positive regulation of triglyceride lipase activity [inference]

positive regulation of lipoprotein lipase activity

regulation of transferase activity [inference]

positive regulation of transferase activity [inference]

positive regulation of CoA-transferase activity

regulation of CoA-transferase activity [inference]

positive regulation of CoA-transferase activity

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

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GO Term	Evidence Code	PMID
high-density lipoprotein particle	IBA IDA	3095477
low-density lipoprotein particle	IBA
blood microparticle	HDA	22516433
very-low-density lipoprotein particle	IBA IDA	17154273 3095477
synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

triglyceride-rich plasma lipoprotein particle [inference]

very-low-density lipoprotein particle

chylomicron

cellular anatomical entity [inference]

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

blood microparticle

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GO Term	Evidence Code	PMID
lipid transporter activity	TAS	3080432
antioxidant activity	IDA	16945374
phospholipid binding	IBA
phosphatidylcholine-sterol O-acyltransferase activator activity	IBA IDA	1935934
phosphatidylcholine binding	IDA	11940599 1935934

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity

sterol transporter activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

lipid binding

phospholipid binding

phosphatidylcholine binding

ion binding [inference]

cation binding [inference]

phosphatidylcholine binding

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

antioxidant activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

phosphatidylcholine-sterol O-acyltransferase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

phosphatidylcholine-sterol O-acyltransferase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Apolipoprotein Eb

Functional Category

L: Replication, recombination and repair
N: Cell motility
T: Signal transduction mechanisms

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Gene Ontology
cholesterol efflux
lipid binding
lipid transport
lipoprotein metabolic process
phosphatidylcholine binding
phosphatidylcholine-sterol O-acyltransferase activator activity
phospholipid efflux
positive regulation of fatty acid biosynthetic process
positive regulation of triglyceride catabolic process
triglyceride homeostasis

Displaying 1 entry
InterPro
Apolipoprotein A/E

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0060180	colitis	Alliance of Genome Resources
DOID:0081267	graft-versus-host disease	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:12842	Guillain-Barre syndrome	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:1287	cardiovascular system disease	Alliance of Genome Resources
DOID:1389	polyneuropathy	Alliance of Genome Resources
DOID:1470	major depressive disorder	Alliance of Genome Resources
DOID:1686	glaucoma	Alliance of Genome Resources
DOID:2378	relapsing-remitting multiple sclerosis	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	11808		MGI:88051	MOUSE63361
Rattus norvegicus	25080		RGD:2132	RATNO39760
Danio rerio	322543		ZFIN:ZDB-GENE-030131-1263
Sus scrofa	397681			PIGXX35459
Xenopus laevis	399000		Xenbase:XB-GENE-17334798
Pan troglodytes	466792	9598_0:003136		PANTR48472
Xenopus tropicalis	493461		Xenbase:XB-GENE-941908
Xenopus laevis	494693		Xenbase:XB-GENE-941913
Danio rerio	550608		ZFIN:ZDB-GENE-050417-469
Danio rerio	570354		ZFIN:ZDB-GENE-030131-3143

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements