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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
G protein-coupled bile acid receptor 1
Summary
- Gene Symbol
-
- Gpbar1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of bicellular tight junction assembly | ||
| cell surface bile acid receptor signaling pathway | ||
| cellular response to bile acid | ||
| G protein-coupled receptor signaling pathway | ||
| positive regulation of ERK1 and ERK2 cascade |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex | ||
| plasma membrane | ||
| cytoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled bile acid receptor activity | ||
| G protein-coupled receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- G-protein coupled bile acid receptor 1
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled bile acid receptor activity |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:0080547 | metabolic dysfunction-associated steatohepatitis | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:898 | autosomal dominant polycystic kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101089457 | FELCA21627 | |||
| 101124421 | GORGO25869 | |||
| 101561982 | 10160_0:0038c1 | OCTDE19864 | ||
| 101615550 | 51337_0:0016c4 | JACJA14492 | ||
| 101680615 | MUSPF08985 | |||
| 101710900 | 10181_0:003958 | HETGA16913 | ||
| 101829686 | 10036_0:0028b7 | |||
| 101957544 | 43179_0:002d89 | ICTTR17162 | ||
| 101999909 | 79684_0:00336d | |||
| 102014529 | 34839_0:0029e6 | CHILA14083 |
