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nervana 2

Summary

Gene Symbol

nrv2

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33953

PubChem

33953

Alliance of Genome Resources

FB:FBgn0015777

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Signal-anchor
Sodium/potassium transport
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q24048	Protein nervana 2 Sodium/potassium-dependent ATPase subunit beta-2
A4V0B5
Q1RL12

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
monoatomic cation transport	IDA	9648860
regulation of tube diameter, open tracheal system	IMP	12930776
intracellular sodium ion homeostasis	IBA
establishment of glial blood-brain barrier	IMP	16213218 18199760
regulation of tube size, open tracheal system	IMP	10887083

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell adhesion involved in heart morphogenesis

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

tight junction organization [inference]

tight junction assembly [inference]

septate junction assembly

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

system development [inference]

respiratory system development [inference]

open tracheal system development

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

biological regulation [inference]

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system [inference]

regulation of tube size, open tracheal system

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube size, open tracheal system

regulation of tube diameter [inference]

regulation of tube diameter, open tracheal system

Displaying **all 4** entries
GO Term	Evidence Code	PMID
axon	IDA	25294943
plasma membrane	HDA IDA	19000835 19317464
septate junction	IDA	12782686 17164420
sodium:potassium-exchanging ATPase complex	IBA IDA IEA	9648860

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

septate junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying 1 entry
GO Term	Evidence Code	PMID
ATPase activator activity	IBA IDA	9648860

GO Hierarchy

molecular function

molecular function regulator activity [inference]

ATPase regulator activity [inference]

ATPase activator activity

molecular function activator activity [inference]

ATPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 7** entries
Location	References
axon	PMID:25294943
septate junction	PMID:12782686 PMID:17164420
sodium	PMID:9648860
membrane	FB:FBrf0231198
plasma membrane	PMID:18199760 PMID:19000835 PMID:19317464
cell body	PMID:10452950
cytoplasm	FB:FBrf0161605

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:0040090	autoimmune gastritis	Alliance of Genome Resources
DOID:10003	sensorineural hearing loss	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:10825	essential hypertension	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:8929	atrophic gastritis	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources