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nervana 2

Summary

Gene Symbol

nrv2

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33953

PubChem

33953

Alliance of Genome Resources

FB:FBgn0015777

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Signal-anchor
Sodium/potassium transport
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q24048	Protein nervana 2 Sodium/potassium-dependent ATPase subunit beta-2
A4V0B5
Q1RL12

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
monoatomic cation transport	IDA	9648860
potassium ion transport	IEA
sodium ion transport	IEA
intracellular sodium ion homeostasis	IBA
open tracheal system development	IMP	10887083

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell adhesion involved in heart morphogenesis

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

tight junction organization [inference]

tight junction assembly [inference]

septate junction assembly

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

system development [inference]

respiratory system development [inference]

open tracheal system development

cellular developmental process [inference]

cell development [inference]

glial cell development [inference]

establishment of glial blood-brain barrier

establishment of blood-brain barrier [inference]

establishment of glial blood-brain barrier

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

sodium ion transport

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

biological regulation [inference]

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system [inference]

regulation of tube size, open tracheal system

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube size, open tracheal system

regulation of tube diameter [inference]

regulation of tube diameter, open tracheal system

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
plasma membrane	IDA	19000835
plasma membrane	HDA	19317464
sodium:potassium-exchanging ATPase complex	IDA	9648860
sodium:potassium-exchanging ATPase complex	IBA
sodium:potassium-exchanging ATPase complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

septate junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ATPase activator activity	IDA	9648860
ATPase activator activity	IBA

GO Hierarchy

molecular function

molecular function regulator activity [inference]

ATPase regulator activity [inference]

ATPase activator activity

molecular function activator activity [inference]

ATPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sodium/potassium-transporting ATPase subunit beta

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ATPase activator activity
intracellular sodium ion homeostasis

Displaying **all 2** entries
InterPro
Sodium/potassium-transporting ATPase subunit beta superfamily
Sodium/potassium-transporting ATPase subunit beta

Alliance of Genome Resources

Expression

Displaying **all 7** entries
Location	References
plasma membrane	PMID:18199760 PMID:19000835 PMID:19317464
sodium	PMID:9648860
axon	PMID:25294943
cell body	PMID:10452950
septate junction	PMID:12782686 PMID:17164420
membrane	FB:FBrf0231198
cytoplasm	FB:FBrf0161605

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1826	epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	481	Xenbase:XB-GENE-482813
Danio rerio	482	ZFIN:ZDB-GENE-010718-1
Danio rerio	483	ZFIN:ZDB-GENE-990415-167
Xenopus tropicalis	496	Xenbase:XB-GENE-944891
Xenopus tropicalis	11931	Xenbase:XB-GENE-482813
Danio rerio	11932	ZFIN:ZDB-GENE-010718-1
Danio rerio	11933	ZFIN:ZDB-GENE-990415-167
Xenopus tropicalis	11945	Xenbase:XB-GENE-944891
Xenopus tropicalis	24217	Xenbase:XB-GENE-944891
Danio rerio	25390	ZFIN:ZDB-GENE-990415-167