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coiled-coil domain 39 molecular ruler complex subunit

Summary

Gene Symbol

CCDC39

Organism

Homo sapiens (human)

External Links

NCBI Gene

339829

PubChem

339829

Alliance of Genome Resources

HGNC:25244

JoGo

CCDC39

TogoVar

CCDC39

Annotation

Keyword

3D-structure
Alternative splicing
Cilium
Coiled coil
Cytoskeleton
Kartagener syndrome
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UFE4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
heart looping	IMP	22693285
cilium movement	IMP	22499950
regulation of cilium beat frequency	IMP	23255504
brain development
microglia differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement

epithelial cilium movement involved in extracellular fluid movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

ensheathment of neurons [inference]

axon ensheathment [inference]

axon ensheathment in central nervous system [inference]

central nervous system myelination

myelination [inference]

central nervous system myelination

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell maturation [inference]

neuron maturation

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly [inference]

motile cilium assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly

protein-containing complex assembly [inference]

axonemal dynein complex assembly

inner dynein arm assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly [inference]

motile cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly

cell junction organization [inference]

synapse organization [inference]

synapse maturation

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

axonemal dynein complex assembly

inner dynein arm assembly

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cerebrospinal fluid circulation

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

embryonic morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

developmental maturation [inference]

synapse maturation

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation

anatomical structure development [inference]

cerebral cortex development

animal organ development [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

glial cell differentiation [inference]

microglia differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation [inference]

microglia differentiation

cell maturation [inference]

neuron maturation

locomotion

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

establishment of localization in cell

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement [inference]

regulation of cilium beat frequency

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
cytosol	IEA
cilium	IDA	27120127
axoneme	IDA	21131972 21131974 26387594
axoneme	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110598	primary ciliary dyskinesia 14	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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