GlyCosmos Portal

Submissions

ATP binding cassette subfamily B member 5

Summary

Gene Symbol

ABCB5

Organism

Homo sapiens (human)

External Links

NCBI Gene

340273

PubChem

340273

Alliance of Genome Resources

HGNC:46

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Differentiation
Glycoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2M3G0	ABCB5 P-gp P-glycoprotein ABCB5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
eye development	ISS
transmembrane transport	IBA IDA TAS	12960149
regulation of membrane potential	IDA	12960149
xenobiotic transport	IEA
cell differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

transmembrane transport

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane
apical plasma membrane	IBA
plasma membrane	IDA TAS	12960149

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IEA
ATPase-coupled transmembrane transporter activity	IBA TAS
ABC-type xenobiotic transporter activity	IEA
ATP binding	IEA
efflux transmembrane transporter activity	IDA	12960149

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

efflux transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity [inference]

ABC-type xenobiotic transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity [inference]

ABC-type xenobiotic transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1485	cystic fibrosis	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 51 in total

« First

‹ Prev

1

2

3

4

5

6

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Macaca mulatta	712883			MACMU32031
Pan troglodytes	743269	9598_0:002158		PANTR39785
Danio rerio	798527		ZFIN:ZDB-GENE-030131-6414
Saccharomyces cerevisiae S288C	853671		SGD:S000001692
Oryctolagus cuniculus	100346799			RABIT01506
Callithrix jacchus	100403814			CALJA42712
Pongo abelii	100458668	9601_0:002122		PONAB33606
Ailuropoda melanoleuca	100468402			AILME16729
Nomascus leucogenys	100581390			NOMLE03091
Loxodonta africana	100661700			LOXAF17644

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements